Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Do T2-weighted pulse sequences help with the differential diagnosis of enhancing lesions in dynamic breast MRI?
Autore:
Kuhl, CK; Klaschik, S; Mielcarek, P; Gieseke, J; Wardelmann, E; Schild, HH;
Indirizzi:
Univ Bonn, Dept Radiol, D-53105 Bonn, Germany Univ Bonn Bonn Germany D-53105 Bonn, Dept Radiol, D-53105 Bonn, Germany
Titolo Testata:
JMRI-JOURNAL OF MAGNETIC RESONANCE IMAGING
fascicolo: 2, volume: 9, anno: 1999,
pagine: 187 - 196
SICI:
1053-1807(199902)9:2<187:DTPSHW>2.0.ZU;2-T
Fonte:
ISI
Lingua:
ENG
Soggetto:
PATHOLOGICAL CORRELATION; CONTRAST; BIOPSY; FIBROADENOMAS; CANCER;
Keywords:
breast cancer; MRI; breast cancer/differential diagnosis; T2-weighted pulse sequence; turbo spin-echo imaging;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
23
Recensione:
Indirizzi per estratti:
Indirizzo: Kuhl, CK Univ Bonn, Dept Radiol, Sigmund Freud Str 25, D-53105 Bonn, Germany Univ Bonn Sigmund Freud Str 25 Bonn Germany D-53105 onn, Germany
Citazione:
C.K. Kuhl et al., "Do T2-weighted pulse sequences help with the differential diagnosis of enhancing lesions in dynamic breast MRI?", J MAGN R I, 9(2), 1999, pp. 187-196

Abstract

In this study. our purpose was to determine whether T2-weighted images area useful diagnostic adjunct for lesion characterization in dynamic breast MRI. On a 1.5-T system, 205 enhancing benign and malignant breast tumors were examined, The standardized protocol consisted of a T2-weighted turbo spin echo (TSE) pulse sequence with and without spectral fat suppression (SPIR), followed by a two-dimensional dynamic series with subtraction postprocessing. In 59 cases, T2*-weighted gradient-echo images also were obtained. Two independent radiologists visually rated the lesions (101 malignant, 104 benign) as having either a low or a high signal with respect to the adjacentglandular tissue. To assess age dependency of lesion enhancement velocities and T2-TSE signal intensities, we compared the results for patients at orbelow the age of 50 (group A), between 40 and 50 (group B), and beyond theage of 50 (group C). In Ta-weighted TSE images, breast cancers were iso- or hypointense with respect to breast parenchyma in 87% of cases, whereas fibroadenomas were hyperintense in 71%, Visual assessment of lesion appearance in T2-weighted TSE images allowed to distinguish between fibroadenomas and breast cancers, with a respective sensitivity, specificity, positive predictive value, and negative predictive value of 72%. 75%, 46%, and 90% for young patients; 94%, 66%, 78%, and 89% for the patients between 40 and 50; and 80%, 62%, 85%, and 68% for the patients over 50 years of age. No significant difference was found for the distribution of signal intensities of lesions in T2*-weighted images or in fat-suppressed images. In a contrast-enhancing breast lesion, careful analysis of T2-weighted TSE Images can improvedifferential diagnosis, The accuracy of this criterion varies with age. J,Magn, Reson, Imaging 1999;9:187-196, (C) 1999 Wiley-Liss, Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/11/20 alle ore 07:05:30