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Titolo:
Parenteral nutrition following intensive cytotoxic therapy: an exploratorystudy on the need for parenteral nutrition after various treatment approaches for haematological malignancies
Autore:
Iestra, JA; Fibbe, WE; Zwinderman, AH; Romijn, JA; Kromhout, D;
Indirizzi:
Leiden Univ, Med Ctr, Dept Nutr & Dietet, Bilthoven, Netherlands Leiden Univ Bilthoven Netherlands Nutr & Dietet, Bilthoven, Netherlands Leidendsniv, Med Ctr, Dept Internal Med, Div Haematol, Bilthoven, Netherlan Leiden Univ Bilthoven Netherlands d, Div Haematol, Bilthoven, Netherlan Leiden Univ, Dept Med Stat, Bilthoven, Netherlands Leiden Univ BilthovenNetherlands Dept Med Stat, Bilthoven, Netherlands Natl Inst Publ Hlth & Environm, NL-3720 BA Bilthoven, Netherlands Natl Inst Publ Hlth & Environm Bilthoven Netherlands NL-3720 BA herlands
Titolo Testata:
BONE MARROW TRANSPLANTATION
fascicolo: 9, volume: 23, anno: 1999,
pagine: 933 - 939
SICI:
0268-3369(199905)23:9<933:PNFICT>2.0.ZU;2-H
Fonte:
ISI
Lingua:
ENG
Soggetto:
BONE-MARROW TRANSPLANTATION; BODY-COMPOSITION; RECIPIENTS;
Keywords:
parenteral nutrition; leukaemia; lymphoma; cancer chemotherapy; bone marrow transplantation;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
22
Recensione:
Indirizzi per estratti:
Indirizzo: Iestra, JA Univetherlandsosp, Ctr Rehabil & Nutr Sci, POB 85500, NL-3508 GA Utrecht, N Univ Utrecht Hosp POB 85500 Utrecht Netherlands NL-3508 GA , N
Citazione:
J.A. Iestra et al., "Parenteral nutrition following intensive cytotoxic therapy: an exploratorystudy on the need for parenteral nutrition after various treatment approaches for haematological malignancies", BONE MAR TR, 23(9), 1999, pp. 933-939

Abstract

Patients receiving intensive cytotoxic therapy are traditionally supportedwith parenteral nutrition (PN), although it is unclear whether all patients benefit from PN, This study aimed to identify regimen-associated differences in PN requirements, to reveal discrepancies between the number of PN indications and the frequency,vith which PN was actually given, and to describe characteristics of patients who met nutritional goals without PN, PN indications were defined as: (1) severe malnutrition at admission; (2)a prolonged period (7-10 days) of minimal oral intake; or (3) clinical weight loss >10%. PN was found to be needed in only 35% of consolidation courses, compared with 80% during remission induction and 55% during BMT, Significant differences were also seen between BMT protocols: PN was required in only 37% of autologous BMT recipients conditioned without total body irradiation (for lymphoma) vs 92% of recipients of a mismatched graft. A high body mass index was the only significant characteristic of patients who could do without PN. In conclusion, PN is not required for all patients undergoing intensive cytotoxic therapy. Screening of nutritional status at the start of therapy and monitoring oral intake following cytotoxic treatment may allow more appropriate identification of patients requiring PN.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 01/04/20 alle ore 23:36:13