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Titolo:
NEONATAL SYMPTOMATIC THROMBOEMBOLISM IN GERMANY - 2-YEAR SURVEY
Autore:
NOWAKGOTTL U; VONKRIES R; GOBEL U;
Indirizzi:
UNIV MUNSTER,UNIV CHILDRENS HOSP,DEPT PAEDIAT HAEMATOL ONCOL,ALBERT SCHWEITZER STR 33 D-48149 MUNSTER GERMANY UNIV HOSP MUNSTER,DEPT PAEDIAT MUNSTER GERMANY UNIV HOSP MUNICH MUNICH GERMANY UNIV HOSP DUSSELDORF DUSSELDORF GERMANY
Titolo Testata:
Archives of Disease in Childhood
fascicolo: 3, volume: 76, anno: 1997,
pagine: 163 - 167
SICI:
0003-9888(1997)76:3<163:NSTIG->2.0.ZU;2-9
Fonte:
ISI
Lingua:
ENG
Soggetto:
HEMOSTATIC SYSTEM; THROMBOSIS; COMPLICATIONS; CHILDHOOD; CHILDREN;
Keywords:
THROMBOEMBOLISM; DOPPLER ULTRASONOGRAPHY; HEPARIN; THROMBOLYTIC AGENTS; GERMANY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
16
Recensione:
Indirizzi per estratti:
Citazione:
U. Nowakgottl et al., "NEONATAL SYMPTOMATIC THROMBOEMBOLISM IN GERMANY - 2-YEAR SURVEY", Archives of Disease in Childhood, 76(3), 1997, pp. 163-167

Abstract

Aims-To determine the incidence of neonatal thromboembolism in Germany. Methods-Diagnostic imaging techniques, therapeutic modalities, and short term outcome were evaluated in a prospective nationwide two yearcase registry study. Results-The reported incidence of symptomatic neonatal thromboembolism, diagnosed in most cases with Doppler ultrasonography, was 5.1 per 100 000 births, with a total of 79 cases registered: renal venous thrombosis (n=35); venous thrombosis (n=25); and arterial vascular occlusion (n=19). Fifty seven of 79 thromboses were associated with additional risk factors (central line n=25, asphyxia n = 13, septicaemia n = 11, dehydration n = 6, maternal diabetes n = 2, cardiac disease n = 1). Inherited thrombophilia was also diagnosed in seven out of 35 cases investigated. Twenty three children received supportive treatment: 42 received heparin and in 13 neonates thrombolytic agents were administered. Most neonates (91%) survived; seven died. Conclusion-controlled multicentre studies are needed to obtain more information on treatment efficacy.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 01/12/20 alle ore 22:23:59