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Titolo:
Leukocyte traffic in the central nervous system: the participants and their roles
Autore:
Hickey, WF;
Indirizzi:
DHMC, Dartmouth Med Sch, Dept Pathol, Lebanon, NH 03756 USA DHMC Lebanon NH USA 03756 uth Med Sch, Dept Pathol, Lebanon, NH 03756 USA
Titolo Testata:
SEMINARS IN IMMUNOLOGY
fascicolo: 2, volume: 11, anno: 1999,
pagine: 125 - 137
SICI:
1044-5323(199904)11:2<125:LTITCN>2.0.ZU;2-3
Fonte:
ISI
Lingua:
ENG
Soggetto:
EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS; EXPERIMENTAL ALLERGIC ENCEPHALOMYELITIS; BLOOD-BRAIN-BARRIER; MICROVASCULAR ENDOTHELIAL-CELLS; MULTIPLE-SCLEROSIS LESIONS; ADHESION MOLECULE-1 ICAM-1; ACTIVATED SPLEEN-CELLS; LYMPHOCYTES IN-VITRO; MYELIN BASIC-PROTEIN; DEVELOPING RAT-BRAIN;
Keywords:
adhesion molecules; B lymphocytes; leukocyte migration; macrophage; monocytes; T lymphocytes;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
106
Recensione:
Indirizzi per estratti:
Indirizzo: Hickey, WF DHMC, Dartmouth Med Sch, Dept Pathol, Lebanon, NH 03756 USA DHMC Lebanon NH USA 03756 , Dept Pathol, Lebanon, NH 03756 USA
Citazione:
W.F. Hickey, "Leukocyte traffic in the central nervous system: the participants and their roles", SEMIN IMMUN, 11(2), 1999, pp. 125-137

Abstract

While the central nervous system has long been considered immunologically privileged, over the past decade it has become evident that a wide variety of leukocyte types traffic through the nervous system. It is also apparent that the rules governing the trafficking of these disparate cell types are different for each. Some arrive, and probably depart, continuously as part of normal physiology. Others only appear to seek a specific antigen or in response to tissue damage. In this review the nature and function of individual cell types are discussed and our current knowledge regarding the parameters governing their entry into the CNS is examined.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 28/03/20 alle ore 09:23:17