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Titolo:
Cytotoxic polyacetylenes from the marine sponge Petrosia sp.
Autore:
Kim, JS; Lim, YJ; Im, KS; Jung, JH; Shim, CJ; Lee, CO; Hong, J; Lee, H;
Indirizzi:
Pusan Natl Univ, Coll Pharm, Res Inst Drug Dev, Pusan 609735, South Korea Pusan Natl Univ Pusan South Korea 609735 Dev, Pusan 609735, South Korea Han Nam Univ, Dept Biol, Taejon, South Korea Han Nam Univ Taejon South Korea am Univ, Dept Biol, Taejon, South Korea Korea Res Inst Chem Technol, Pharmaceut Screening Ctr, Taejon 305606, South Korea Res Inst Chem Technol Taejon South Korea 305606 ejon 305606, South Korea Basic Sci Inst, Mass Spectrometry Grp, Taejon, South Korea Korea Basic Sci Inst Taejon South Korea ometry Grp, Taejon, South Korea Korean Ocean Res & Dev Inst, Seoul, South Korea Korean Ocean Res & Dev Inst Seoul South Korea Inst, Seoul, South Korea
Titolo Testata:
JOURNAL OF NATURAL PRODUCTS
fascicolo: 4, volume: 62, anno: 1999,
pagine: 554 - 559
SICI:
0163-3864(199904)62:4<554:CPFTMS>2.0.ZU;2-X
Fonte:
ISI
Lingua:
ENG
Soggetto:
MOLECULAR-WEIGHT POLYACETYLENES; BIOACTIVE POLYACETYLENES; ABSOLUTE-CONFIGURATION; CRIBROCHALINA-VASCULUM; ACETYLENIC ALCOHOLS; GENUS PETROSIA; FICIFORMIS; PETROFORMYNES; METABOLITES; INHIBITORS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Agriculture,Biology & Environmental Sciences
Life Sciences
Citazioni:
25
Recensione:
Indirizzi per estratti:
Indirizzo: Jung, JH Pusan Natl Univ, Coll Pharm, Res Inst Drug Dev, Pusan 609735, South Korea Pusan Natl Univ Pusan South Korea 609735 an 609735, South Korea
Citazione:
J.S. Kim et al., "Cytotoxic polyacetylenes from the marine sponge Petrosia sp.", J NAT PROD, 62(4), 1999, pp. 554-559

Abstract

Three C-46 (1--3) and three C-30 (4-6) polyacetylenic alcohols with cytotoxic activity against a small panel of human solid-tumor cell lines have been isolated from the marine sponge Petrosia sp. Although compound 1 was identified as the stereoisomer of petrocortyne A, the structures of compounds 2-5 have not been previously reported and were established by spectral methods. Compound 6 was identified as the known compound petrosiacetylene D. Thestereochemistry of compounds 1-5 was determined by the modified Mosher's method.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 15/07/20 alle ore 08:42:11