Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Prevalence and predictors of squamous cell abnormalities in Papanicolaou smears from women infected with HIV-1
Autore:
Massad, LS; Riester, KA; Anastos, KM; Fruchter, RG; Palefsky, JM; Burk, RD; Burns, D; Greenblatt, RM; Muderspach, LI; Miotti, P;
Indirizzi:
CookUSAy Hosp, Dept Obstet & Gynecol, Div Gynecol Oncol, Chicago, IL 60612Cook Cty Hosp Chicago IL USA 60612 , Div Gynecol Oncol, Chicago, IL 60612 Rush Med Coll, Chicago, IL 60612 USA Rush Med Coll Chicago IL USA 60612Rush Med Coll, Chicago, IL 60612 USA New England Res Inst, Watertown, MA 02172 USA New England Res Inst Watertown MA USA 02172 Inst, Watertown, MA 02172 USA Montefiore Med Ctr, Bronx, NY 10467 USA Montefiore Med Ctr Bronx NY USA 10467 efiore Med Ctr, Bronx, NY 10467 USA State Univ New York Brooklyn, Dept Obstet & Gynecol, Brooklyn, NY USA State Univ New York Brooklyn Brooklyn NY USA & Gynecol, Brooklyn, NY USA Univ Calif San Francisco, San Francisco, CA 94143 USA Univ Calif San Francisco San Francisco CA USA 94143 ancisco, CA 94143 USA Albert Einstein Coll Med, Dept Pediat, Bronx, NY 10467 USA Albert EinsteinColl Med Bronx NY USA 10467 t Pediat, Bronx, NY 10467 USA NICHHD, Pediat Adolescent & Maternal AIDS Branch, Bethesda, MD 20892 USA NICHHD Bethesda MD USA 20892 Maternal AIDS Branch, Bethesda, MD 20892 USA Univ Calif San Francisco, Dept Med, San Francisco, CA USA Univ Calif San Francisco San Francisco CA USA Med, San Francisco, CA USA Univ Calif San Francisco, Dept Epidemiol, San Francisco, CA USA Univ CalifSan Francisco San Francisco CA USA iol, San Francisco, CA USA Univ So Calif, Sch Med, Dept Obstet & Gynecol, Los Angeles, CA 90033 USA Univ So Calif Los Angeles CA USA 90033 Gynecol, Los Angeles, CA 90033 USA NIAID, Div Aids, Bethesda, MD 20892 USA NIAID Bethesda MD USA 20892NIAID, Div Aids, Bethesda, MD 20892 USA
Titolo Testata:
JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES AND HUMAN RETROVIROLOGY
fascicolo: 1, volume: 21, anno: 1999,
pagine: 33 - 41
SICI:
1525-4135(19990501)21:1<33:PAPOSC>2.0.ZU;2-C
Fonte:
ISI
Lingua:
ENG
Soggetto:
HUMAN-IMMUNODEFICIENCY-VIRUS; CERVICAL INTRAEPITHELIAL NEOPLASIA; HUMAN-PAPILLOMAVIRUS INFECTION; RISK-FACTORS; COLPOSCOPY; CANCER; POPULATION; MANAGEMENT; DYSPLASIA; LESIONS;
Keywords:
HIV; cytology; screening; squamous intraepithelial lesion;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
46
Recensione:
Indirizzi per estratti:
Indirizzo: Massad, LS CookUSAy Hosp, Dept Obstet & Gynecol, Div Gynecol Oncol, Chicago, IL 60612 Cook Cty Hosp Chicago IL USA 60612 ol Oncol, Chicago, IL 60612
Citazione:
L.S. Massad et al., "Prevalence and predictors of squamous cell abnormalities in Papanicolaou smears from women infected with HIV-1", J ACQ IMM D, 21(1), 1999, pp. 33-41

Abstract

Cervical neoplasia occurs with increased frequency among women infected with HIV-1. Objective: To characterize prevalence of and risk factors for abnormal cervical cytology among women with HIV and to compare them to uninfected women. Methods: Baseline cervical cytology was obtained from 1713 women seropositive for HIV and 482 at-risk control women who were enrolled in the Women'sInteragency HIV Study, a multicenter prospective cohort study conducted insix U.S. cities. Associations with sociodemographic, medical, and sexual variables were assessed by Fisher's exact test, Mantel extension test, and logistic regression analysis. Results: Cervical cytology was abnormal in 38.3% of HIV-infected women (atypical squamous cells of uncertain significance [ASCUS] 20.9%, low-grade squamous cells of uncertain significance [LSIL] 14.9%, high-grade squamous cells of uncertain significance [HSIL] 2.3%, cancer 0.2%) and 16.2% of HIV-uninfected women (ASCUS 12.7%, LSIL 2.3%, HSIL 1.2%, cancer 0.0%). Risk factors for any abnormal cytology in multivariate analysis included HIV infection, CD4 cell count, HIV RNA level, detection of human papillomavirus (HPV), a prior history of abnormal cytology, employment, and number of male sex partners within 6 months of enrollment. Prior abortion was associated with a decreased risk of cytologic abnormality. Conclusions: Cervical cytologic abnormalities were frequent among women infected with HIV, although high-grade changes were found in only 2.5%. Factors linked to sexual and reproductive history, HPV infection, and HIV disease all influenced risk.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 28/01/21 alle ore 07:33:17