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Titolo:
Effects of subcortical cerebrovascular lesions on cortical hemodynamic parameters assessed by perfusion magnetic resonance imaging
Autore:
Nighoghossian, N; Berthezene, Y; Adeleine, P; Wiart, M; Damien, J; Derex, L; Itti, R; Froment, JC; Trouillas, P;
Indirizzi:
CNRS, UMR 5515, CREATIS, Cerebrovasc Dis & Ataxia Res Ctr, Lyon, France CNRS Lyon France REATIS, Cerebrovasc Dis & Ataxia Res Ctr, Lyon, France CNRS, UMR 5515, CREATIS, Dept Radiol, Lyon, France CNRS Lyon FranceCNRS, UMR 5515, CREATIS, Dept Radiol, Lyon, France Biostat Unit, Lyon, France Biostat Unit Lyon FranceBiostat Unit, Lyon, France Dept Nucl Med, Lyon, France Dept Nucl Med Lyon FranceDept Nucl Med, Lyon, France
Titolo Testata:
CEREBROVASCULAR DISEASES
fascicolo: 3, volume: 9, anno: 1999,
pagine: 136 - 141
SICI:
1015-9770(199905/06)9:3<136:EOSCLO>2.0.ZU;2-A
Fonte:
ISI
Lingua:
ENG
Soggetto:
POSITRON EMISSION TOMOGRAPHY; CEREBRAL BLOOD-FLOW; THALAMIC STROKE; OXYGEN-METABOLISM; APHASIA; NEGLECT; DIASCHISIS; CORTEX; PET;
Keywords:
subcortical stroke; cortical blood volume and blood flow; dynamic susceptibility contrast-enhanced MRI;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
31
Recensione:
Indirizzi per estratti:
Indirizzo: Nighoghossian, N Hopceeurol, Serv Neurol, Ctr Rech Ataxie, 59 Blvd Pinel, F-69003 Lyon, Fran Hop Neurol 59 Blvd Pinel Lyon France F-69003 Lyon, Fran
Citazione:
N. Nighoghossian et al., "Effects of subcortical cerebrovascular lesions on cortical hemodynamic parameters assessed by perfusion magnetic resonance imaging", CEREB DIS, 9(3), 1999, pp. 136-141

Abstract

A simultaneous decrease of cerebral blood volume (CBV) and cerebral blood flow (CBF) has been described after subcortical stroke with positron emission tomography, However, this imaging modality cannot be applied routinely to stroke patients. Dynamic susceptibility contrast-enhanced MRI techniques (DSC-MRI) might be interesting in the assessment of these effects. Dynamic T-2-weighted echo planar imaging was used to produce DSC-MR images during an intravenous bolus injection of gadopentetate dimeglumine in 9 patients who experienced a subcortical stroke involving thalamus or basal ganglia and in 8 control subjects. A series of 50 consecutive images at 1-second intervals was acquired at the anatomic level of the centrum semiovale quite distant from the subcortical lesion, rCBF and rCBV were determined over frontal and parietal regions of interest and through the entire cortical mantle. DSC-MRI enabled the detection of hemodynamic changes induced by subcortical stroke. Analysis of rCBV and rCBF values showed that the hemodynamic parameters were significantly decreased on the affected side. In controls mean rCBF and rCBV values recorded over the whole cortical mantle of each hemisphere showed no significant interhemispheric asymmetry.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 18/09/20 alle ore 19:14:24