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Titolo:
Longitudinal and lateral variations in the aluminum concentration of selected caprine, bovine, and human bone samples
Autore:
Tang, S; Parsons, PJ; Perl, D;
Indirizzi:
New York State Dept Hlth, Wadsworth Ctr, Albany, NY 12201 USA New York State Dept Hlth Albany NY USA 12201 th Ctr, Albany, NY 12201 USA SUNYUSAbany, Sch Publ Hlth, Dept Environm Hlth & Toxicol, Albany, NY 12201SUNY Albany Albany NY USA 12201 Environm Hlth & Toxicol, Albany, NY 12201 Mt Sinai Med Ctr, Div Neuropathol, New York, NY 10029 USA Mt Sinai Med Ctr New York NY USA 10029 europathol, New York, NY 10029 USA
Titolo Testata:
BIOLOGICAL TRACE ELEMENT RESEARCH
fascicolo: 3, volume: 68, anno: 1999,
pagine: 267 - 279
SICI:
0163-4984(199906)68:3<267:LALVIT>2.0.ZU;2-Y
Fonte:
ISI
Lingua:
ENG
Soggetto:
ATOMIC-ABSORPTION SPECTROMETRY; DIALYSIS ENCEPHALOPATHY; HEMODIALYZED PATIENTS; PARENTERAL-NUTRITION; ELECTRON-MICROPROBE; CLINICAL-SAMPLES; HUMAN-TISSUES; ILIAC BONE; OSTEOMALACIA; DISEASE;
Keywords:
aluminum distribution; bone analysis; electrothermal atomization-atomic absorption spectrometry; microwave digestion;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
45
Recensione:
Indirizzi per estratti:
Indirizzo: Parsons, PJ New York State Dept Hlth, Wadsworth Ctr, POB 509, Albany, NY 12201 USA New York State Dept Hlth POB 509 Albany NY USA 12201 12201 USA
Citazione:
S. Tang et al., "Longitudinal and lateral variations in the aluminum concentration of selected caprine, bovine, and human bone samples", BIOL TR EL, 68(3), 1999, pp. 267-279

Abstract

Longitudinal and lateral variations in Al concentration in several large animal (bovine and caprine) long bones (tibia and femur) and several human clavicle bones were examined using a sensitive analytical method based on electrothermal atomization atomic absorption spectrometry with Zeeman background correction. Bone segments were carefully removed using special tools free of significant Al contamination, freeze-dried, and digested overnight atroom temperature in concentrated HNO3. Bone digestates were analyzed for Al using simple aqueous calibration standards with a Ca(NO3)(2) modifier. Mean bone Al concentrations were relatively low (<1 mu g/g, dry weight) in bovine and caprine long bones compared to literature values for human bone samples. Longitudinal variations of Al in the animal bones examined appeared relatively uniform compared to the human clavicle bones, where, in three offive cases, Al appeared enriched at the epiphyses (joints). The Al "enrichment" was symmetrical with respect to both left and right clavicle bones. Aluminum concentrations at the mid-shaft of the clavicle bone show less variation compared to whole bone studies, but considerable scatter is evident along the bone length. The mean bone aluminum concentration in the five human subjects varied from 1 to 6 mu g/g dry weight.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 28/03/20 alle ore 23:07:49