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Titolo:
Lipoprotein alterations, abdominal fat distribution and breast cancer
Autore:
Schreier, LE; Berg, GA; Basilio, FM; Lopez, GI; Etkin, AE; Wikinski, RL;
Indirizzi:
Univchem,os Aires, Fac Farm & Bioquim, Lab Lipids & Lipoprot, Dept Clin Bio Univ Buenos Aires Buenos Aires DF Argentina RA-1113 poprot, Dept Clin Bio Hosp CG Durand, Gynecol Serv, Buenos Aires, DF, Argentina Hosp CG Durand Buenos Aires DF Argentina rv, Buenos Aires, DF, Argentina
Titolo Testata:
BIOCHEMISTRY AND MOLECULAR BIOLOGY INTERNATIONAL
fascicolo: 4, volume: 47, anno: 1999,
pagine: 681 - 690
SICI:
1039-9712(199904)47:4<681:LAAFDA>2.0.ZU;2-C
Fonte:
ISI
Lingua:
ENG
Soggetto:
SERUM-LIPIDS; PLASMA-LIPIDS; WOMEN; RISK; OBESITY; DISEASE; APOLIPOPROTEINS; PRECIPITATION; CHOLESTEROL;
Keywords:
breast cancer; lipids; lipoproteins; abdominal obesity;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
27
Recensione:
Indirizzi per estratti:
Indirizzo: Schreier, LE Univchem,os Aires, Fac Farm & Bioquim, Lab Lipids & Lipoprot,Dept Clin Bio Univ Buenos Aires Buenos Aires DF Argentina RA-1113 Clin Bio
Citazione:
L.E. Schreier et al., "Lipoprotein alterations, abdominal fat distribution and breast cancer", BIOC MOL B, 47(4), 1999, pp. 681-690

Abstract

Plasma lipid profile and abdominal obesity have been associated with breast cancer risk, however published results have been inconsistent. To clarifythese associations we studied lipid and lipoprotein alterations, obesity degree and body fat distribution, in 30 newly diagnosed breast cancer patients without treatment and 30 controls matched by age and menopausal status. Both pre and postmenopausal breast cancer patients presented higher body mass index, waist/hip ratio and insulin levels than their matched controls. An increase in triglycerides and a decrease in HDL-cholesterol, especially in the HDL2 subfraction, were observed in patients with breast cancer. Besides, HDL particle from these patients showed increased apo A(1)/HDL-cholesterol ratio. These alterations were correlated with waist/hip ratio. The association between lipoprotein alterations and abdominal obesity independent of menopausal status, in untreated newly diagnosed breast cancer patients is reported for the first time in this study.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 12/07/20 alle ore 09:40:36