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Titolo:
INHIBITION OF A PORPHYROMONAS-GINGIVALIS COLONIZING FACTOR BETWEEN ACTINOMYCES-VISCOSUS ATCC-19246 BY MONOCLONAL-ANTIBODIES AGAINST RECOMBINANT 40-KDA OUTER-MEMBRANE PROTEIN
Autore:
SAITO S; HIRATSUKA K; HAYAKAWA M; TAKIGUCHI H; ABIKO Y;
Indirizzi:
NIHON UNIV,SCH DENT,DEPT BIOCHEM,2-870-1 SAKAECHO NISHI MATSUDO CHIBA271 JAPAN
Titolo Testata:
General pharmacology
fascicolo: 5, volume: 28, anno: 1997,
pagine: 675 - 680
SICI:
0306-3623(1997)28:5<675:IOAPCF>2.0.ZU;2-6
Fonte:
ISI
Lingua:
ENG
Soggetto:
BLACK-PIGMENTED BACTEROIDES; PERIODONTAL-DISEASE; COLONIZATION; VESICLES; ASACCHAROLYTICUS; HEMAGGLUTININ; PURIFICATION; PROTEASES; FIMBRIAE; ADHESION;
Keywords:
PORPHYROMONAS GINGIVALIS; MONOCLONAL ANTIBODY AGAINST RECOMBINANT OUTER-MEMBRANE PROTEIN; COLONIZING FACTOR; PERIODONTAL DISEASES;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
31
Recensione:
Indirizzi per estratti:
Citazione:
S. Saito et al., "INHIBITION OF A PORPHYROMONAS-GINGIVALIS COLONIZING FACTOR BETWEEN ACTINOMYCES-VISCOSUS ATCC-19246 BY MONOCLONAL-ANTIBODIES AGAINST RECOMBINANT 40-KDA OUTER-MEMBRANE PROTEIN", General pharmacology, 28(5), 1997, pp. 675-680

Abstract

1. Porphyromonas gingivalis, an important pathogen in human periodontal disease, aggregates with Actinomyces viscosus ATCC 19246. 2. Monoclonal antibodies (mAbs) against purified recombinant 40-kDa outer membrane protein (r40-kDa OMP) of P. gingivalis 381 inhibited its coaggregation with A. viscosus ATCC 19246 in a dose-dependent manner. 3. Five mAb clones against r40-kDa OMP were selected. The isotype of the five was IgG1. 4. Pg-ompA2 inhibited the coaggregation of several strains ofP. gingivalis with A. viscosus ATCC 19246 cells. (C) 1997 Elsevier Science Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 28/11/20 alle ore 03:35:21