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Titolo:
An approach to anti-HIV-1 active Calophyllum coumarin synthesis: An enantioselective construction of 2,3-dimethyl-4-chromanone ring by quinine-assisted intramolecular Michael-type addition
Autore:
Ishikawa, T; Oku, Y; Tanaka, T; Kumamoto, T;
Indirizzi:
Chiba Univ, Fac Pharmaceut Sci, Chiba 2638522, Japan Chiba Univ Chiba Japan 2638522 Fac Pharmaceut Sci, Chiba 2638522, Japan
Titolo Testata:
TETRAHEDRON LETTERS
fascicolo: 19, volume: 40, anno: 1999,
pagine: 3777 - 3780
SICI:
0040-4039(19990507)40:19<3777:AATAAC>2.0.ZU;2-X
Fonte:
ISI
Lingua:
ENG
Soggetto:
TREE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Physical, Chemical & Earth Sciences
Citazioni:
18
Recensione:
Indirizzi per estratti:
Indirizzo: Ishikawa, T Chiba Univ, Fac Pharmaceut Sci, 1-33 Yayoi Cho, Chiba 2638522,Japan Chiba Univ 1-33 Yayoi Cho Chiba Japan 2638522 2638522, Japan
Citazione:
T. Ishikawa et al., "An approach to anti-HIV-1 active Calophyllum coumarin synthesis: An enantioselective construction of 2,3-dimethyl-4-chromanone ring by quinine-assisted intramolecular Michael-type addition", TETRAHEDR L, 40(19), 1999, pp. 3777-3780

Abstract

(-)-Quinine effectively catalyzes an intramolecular Michael-type addition of 7-hydroxy-8-tigloylcoumarin to give a diastereoisomeric mixture of the corresponding cyclized coumarin with a 2,3-dimethyl-4-chromanone skeleton. Satisfactory enantioselectivity was observed in a cis-chromanone construction, but not in a trans-one. (C) 1999 Elsevier Science Ltd. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/01/20 alle ore 15:40:35