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Titolo:
Studies toward luzopeptins: a key tripeptide subunit selectively deprotectable under neutral conditions
Autore:
Ciufolini, MA; Valognes, D; Xi, N;
Indirizzi:
Univ Lyon 1, F-69622 Villeurbanne, France Univ Lyon 1 Villeurbanne France F-69622 1, F-69622 Villeurbanne, France Ecole Super Chim Phys Elect Lyon, F-69622 Villeurbanne, France Ecole SuperChim Phys Elect Lyon Villeurbanne France F-69622 nne, France Rice Univ, Dept Chem, Houston, TX 77005 USA Rice Univ Houston TX USA 77005 ice Univ, Dept Chem, Houston, TX 77005 USA
Titolo Testata:
TETRAHEDRON LETTERS
fascicolo: 19, volume: 40, anno: 1999,
pagine: 3693 - 3696
SICI:
0040-4039(19990507)40:19<3693:STLAKT>2.0.ZU;2-F
Fonte:
ISI
Lingua:
ENG
Soggetto:
ACID; ANTIBIOTICS; DIPEPTIDE;
Keywords:
luzopeptins; peptides; anti-HIV compounds; azidoacids; N-methyl-3-hydroxyvaline;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Physical, Chemical & Earth Sciences
Citazioni:
17
Recensione:
Indirizzi per estratti:
Indirizzo: Ciufolini, MA Univ Lyon 1, 43 Blvd 11 Novembre 1918, F-69622 Villeurbanne,France Univ Lyon 1 43 Blvd 11 Novembre 1918 Villeurbanne France F-69622
Citazione:
M.A. Ciufolini et al., "Studies toward luzopeptins: a key tripeptide subunit selectively deprotectable under neutral conditions", TETRAHEDR L, 40(19), 1999, pp. 3693-3696

Abstract

We describe a protocol for the multigram preparation of a tripeptide foundin peptin antibiotics. The N-terminus is an azido group, while the C-terminus is an allyl ester, The molecule may be cleanly and selectively deblocked under neutral conditions, facilitating strategic planning for the creation of the macrocyclic sector of all peptins. (C) 1999 Elsevier Science Ltd. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 27/11/20 alle ore 22:09:51