Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Sympathetic mediation of salivation induced by intracerebroventricular pilocarpine in rats
Autore:
Cecanho, R; Anaya, M; Renzi, A; Menani, JV; De Luca, LA;
Indirizzi:
Paulistaaquara,Univ, UNESP, Sch Odontol, Dept Physiol Sci, BR-14801903 Arar Paulista State Univ Araraquara SP Brazil BR-14801903 BC, BR-14801903 Arar
Titolo Testata:
JOURNAL OF THE AUTONOMIC NERVOUS SYSTEM
fascicolo: 1, volume: 76, anno: 1999,
pagine: 9 - 14
SICI:
0165-1838(19990416)76:1<9:SMOSIB>2.0.ZU;2-Z
Fonte:
ISI
Lingua:
ENG
Soggetto:
CENTRAL-NERVOUS-SYSTEM; SECRETION; GLANDS; STIMULATION; INNERVATION; BINDING;
Keywords:
cholinergic receptors; adrenoceptors; cervical ganglion; chorda tympani; salivary glands; lateral ventricle; saliva;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
27
Recensione:
Indirizzi per estratti:
Indirizzo: De Luca, LA Paulista,State Univ, UNESP, Sch Odontol, Dept Physiol Sci, RuaHumaita 1680 Paulista State Univ Rua Humaita 1680 Araraquara SP Brazil BR-14801903 BC
Citazione:
R. Cecanho et al., "Sympathetic mediation of salivation induced by intracerebroventricular pilocarpine in rats", J AUTON NER, 76(1), 1999, pp. 9-14

Abstract

Central cholinergic activation by pilocarpine induces salivation dependenton the integrity of forebrain areas. The present work investigates the autonomic mediation of this salivation. Pilocarpine (500 nmol/rat) was injected into the lateral ventricle (LV) of tribromoethanol-anesthetized adult male rats. Preweighed cotton balls were inserted into the oral cavity and weighed again 7 min later. ol-adrenoceptor antagonists (3-50 mu mol/kg) prazosin (alpha(1)), yohimbine (alpha(2)) or propranolol (beta) injected intraperitoneally (i.p.) produced, 80%, 20% and 0% inhibition respectively of the LVpilocarpine-induced salivation. Intracerebroventricular injections (160 nmol) of the antagonists did not alter the effects of pilocarpine injected into the LV. Bilateral section of chorda tympani nerve or bilateral sympathetic cervical ganglionectomy produced 0% and 40% inhibition of pilocarpine-induced salivation, respectively. Ganglionectomy did not alter salivation induced by i.p, injection of pilocarpine (4 mu mol/kg). The results indicate that there is a large sympathetic contribution to the salivation induced by central cholinergic activation. (C) 1999 Elsevier Science B.V. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 27/11/20 alle ore 02:26:06