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Titolo:
Maturation of medial efferent system function in humans
Autore:
Abdala, C; Ma, E; Sininger, YS;
Indirizzi:
Childrens Auditory Res & Evaluat Ctr, House Ear Inst, Los Angeles, CA 90057 Childrens Auditory Res & Evaluat Ctr Los Angeles CA USA 90057 s, CA 90057
Titolo Testata:
JOURNAL OF THE ACOUSTICAL SOCIETY OF AMERICA
fascicolo: 4, volume: 105, anno: 1999,
pagine: 2392 - 2402
SICI:
0001-4966(199904)105:4<2392:MOMESF>2.0.ZU;2-8
Fonte:
ISI
Lingua:
ENG
Soggetto:
COCHLEAR MICROMECHANICAL PROPERTIES; PRODUCT OTOACOUSTIC EMISSIONS; CROSSED OLIVOCOCHLEAR BUNDLE; ACOUSTIC DISTORTION PRODUCTS; COMPOUND ACTION-POTENTIALS; AUDITORY BRAIN-STEM; ELECTRICAL-STIMULATION; CONTRALATERAL SOUND; SYNAPTIC TRANSMISSION; TUNING CURVES;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Engineering, Computing & Technology
Citazioni:
56
Recensione:
Indirizzi per estratti:
Indirizzo: Abdala, C Childrensgeles,ory Res & Evaluat Ctr, House Ear Inst, 2100 W 3rdSt, Los An Childrens Auditory Res & Evaluat Ctr 2100 W 3rd St Los Angeles CA USA 90057
Citazione:
C. Abdala et al., "Maturation of medial efferent system function in humans", J ACOUST SO, 105(4), 1999, pp. 2392-2402

Abstract

Otoacoustic emissions are typically reduced in amplitude when broadband noise is presented to the contralateral ear. This contralateral suppression is attributed to activation of the medial olivocochlear system, which has aninhibitory effect on outer hair-cell activity. By studying the effects of contralateral noise on cochlear output at different stages of auditory maturation in human neonates, it is possible to describe the timecourse for development of medial efferent system function in humans. The present study recorded 2f1-f2 distortion product otoacoustic emissions (DPOAE) in human adults, term and premature neonates at three f2 frequencies: 1500, 3000, and 6000 Hz, using fixed primary tone frequency ratio (f2/f1 = 1.2) and level separation (10 dB, L1 > L2). Average DPOAE growth functions were recorded with and without contralateral broadband noise. Results indicate that contralateral suppression of DPOAEs is absent at 6000 Hz, but present at 1500 and 3000 Hz for all ages. However, DPOAE amplitude from premature neonates was not altered by noise in an adult-like manner; in this age group, DPOAE amplitude was equally likely to be suppressed or enhanced by noise presented contralaterally. Contralateral enhancement may reflect a temporary stage of immaturity in outer hair cell-medial efferent fiber synapses just prior to term birth. (C) 1999 Acoustical Society of America. [S0001-4966(99)04504-X].

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 28/11/20 alle ore 12:57:26