Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Supratentorial cavernous haemangiomas and epilepsy: a review of the literature and case series
Autore:
Moran, NF; Fish, DR; Kitchen, N; Shorvon, S; Kendall, BE; Stevens, JM;
Indirizzi:
Inst Neurol, Epilepsy Res Grp, London WC1N 3BG, England Inst Neurol London England WC1N 3BG sy Res Grp, London WC1N 3BG, England
Titolo Testata:
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
fascicolo: 5, volume: 66, anno: 1999,
pagine: 561 - 568
SICI:
0022-3050(199905)66:5<561:SCHAEA>2.0.ZU;2-5
Fonte:
ISI
Lingua:
ENG
Soggetto:
CENTRAL-NERVOUS-SYSTEM; OCCULT VASCULAR MALFORMATIONS; NATURAL-HISTORY; CHROMOSOME 7Q; ANGIOMAS; CHILDREN; RADIOSURGERY; SURGERY; BRAIN; LESIONECTOMY;
Keywords:
cavernous haemangioma epilepsy; magnetic resonance imaging; treatment; haemorrhage;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
74
Recensione:
Indirizzi per estratti:
Indirizzo: Moran, NF Inst Neurol, Epilepsy Res Grp, 33 Queen Sq, London WC1N 3BG, England Inst Neurol 33 Queen Sq London England WC1N 3BG 1N 3BG, England
Citazione:
N.F. Moran et al., "Supratentorial cavernous haemangiomas and epilepsy: a review of the literature and case series", J NE NE PSY, 66(5), 1999, pp. 561-568

Abstract

Objectives-To characterise the clinical features and response to treatmentof supratentorial cavernomas associated with epilepsy. Methods-A systematic review of the literature was carried out and a retrospective case series of patients with cavernoma diagnosed by MRI and/or histology was compiled. Patient selection biases in the literature review were reduced as far as possible by selection of unbiased publications. Results-In the literature, cavernomas were relatively less common in the frontal lobes. There were multiple cavernomas in 23% of cases. The main clinical manifestations were seizures (79%) and haemorrhage (16%). The annual haemorrhage rate was 0.7%. The outcome after excision was good with improvement in seizures in 92% of patients. In the case series the surgical outcomewas less favourable, reflecting inclusion of a higher proportion of patients with inh actable epilepsy. In both the literature review and the case series, outcome was poorer in cases with a longer duration of seizures at thetime of surgery. Conclusions-The good surgical results, particularly in cases treated earlier, and the significant cumulative haemorrhage rate, suggest that excision is the optimum treatment. However, these factors have not been examined prospectively and, despite the availability of several retrospective studies, the optimum treatment, particularly for non-intractable cases, will only bedetermined by a prospective study.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 22/09/20 alle ore 09:31:42