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Titolo:
Technique for construction of an in vivo model of simulated pulmonary metastases
Autore:
Johnson, MS; Coakley, FV; Carmody, TJ; Dreesen, RG; Cohen, MD;
Indirizzi:
Univ Calif San Francisco, Dept Radiol, San Francisco, CA 94143 USA Univ Calif San Francisco San Francisco CA USA 94143 ancisco, CA 94143 USA Indiana Univ, Sch Med, Dept Radiol, Indianapolis, IN 46202 USA Indiana Univ Indianapolis IN USA 46202 Radiol, Indianapolis, IN 46202 USA Iowa Methodist Med Ctr, Dept Radiol, Des Moines, IA USA Iowa Methodist MedCtr Des Moines IA USA Dept Radiol, Des Moines, IA USA Indiana Univ, Med Ctr, Dept Radiol, Indianapolis, IN 46204 USA Indiana Univ Indianapolis IN USA 46204 Radiol, Indianapolis, IN 46204 USA
Titolo Testata:
INVESTIGATIVE RADIOLOGY
fascicolo: 5, volume: 34, anno: 1999,
pagine: 336 - 340
SICI:
0020-9996(199905)34:5<336:TFCOAI>2.0.ZU;2-R
Fonte:
ISI
Lingua:
ENG
Soggetto:
SPIRAL CT; NODULES;
Keywords:
animal models disease; pulmonary metastases; pulmonary nodules; computed tomography;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
20
Recensione:
Indirizzi per estratti:
Indirizzo: Coakley, FV UnivnCalif San Francisco, Dept Radiol, 505 Parnassus Ave,Box 0628 L-308, Sa Univ Calif San Francisco 505 Parnassus Ave,Box 0628 L-308 SanFrancisco CA USA 94143
Citazione:
M.S. Johnson et al., "Technique for construction of an in vivo model of simulated pulmonary metastases", INV RADIOL, 34(5), 1999, pp. 336-340

Abstract

RATIONALE AND OBJECTIVES. Existing methods used to simulate pulmonary metastases are unsatisfactory. The aim of this study was to create a simple in vivo model of pulmonary metastases by endobronchial deployment of small high-density heads in anesthetized dogs. METHODS. Commercially available decorative beads measuring 2 and 4 mm in diameter and of high density (600 to 1200 Hounsfield units) mere deployed inthe peripheral airways of anesthetized dogs using catheter and guide wire manipulations through an endotracheal tube. RESULTS. A total of 65 beads were placed in five dogs. Computed tomographydemonstrated that 41 (63%) were satisfactorily located in the lung periphery, 9 (14%) were unsatisfactorily located in large airways, and 15 (23%) were not visible,CONCLUSIONS. The endobronchial deployment of small high-density beads in the peripheral airways of anesthetized dogs is a novel and effective technique for creation of an in vivo model of pulmonary metastases.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 15/07/20 alle ore 21:38:39