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Titolo:
Pediatric liver disease
Autore:
Thompson, R;
Indirizzi:
Guys Kings & St Thomas Sch Med, Dept Child Hlth, London SE5 9RS, England Guys Kings & St Thomas Sch Med London England SE5 9RS n SE5 9RS, England
Titolo Testata:
CURRENT OPINION IN GASTROENTEROLOGY
fascicolo: 3, volume: 15, anno: 1999,
pagine: 249 - 252
SICI:
0267-1379(199905)15:3<249:PLD>2.0.ZU;2-#
Fonte:
ISI
Lingua:
ENG
Soggetto:
FAMILIAL INTRAHEPATIC CHOLESTASIS; EXTRAHEPATIC BILIARY ATRESIA; DUBIN-JOHNSON-SYNDROME; CHOLEDOCHAL CYSTS; MYCOPHENOLATE-MOFETIL; TACROLIMUS FK506; REOVIRUS TYPE-3; ABC TRANSPORTER; P-GLYCOPROTEIN; IN-VIVO;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
37
Recensione:
Indirizzi per estratti:
Indirizzo: Thompson, R GuysnKings & St Thomas Sch Med, Dept Child Hlth, Denmark Hill Campus, Londo Guys Kings & St Thomas Sch Med Denmark Hill Campus London England SE5 9RS
Citazione:
R. Thompson, "Pediatric liver disease", CURR OPIN G, 15(3), 1999, pp. 249-252

Abstract

Pediatric hepatology has advanced greatly over the past few years. Many more children with severe liver disease are now surviving into adulthood. There is a number of conditions not seen in adult practice that have been the focus of research efforts, and many of these efforts have borne fruit in the past year. Disorders characterized by intrahepatic cholestasis in particular have now been substantially unravelled, and this work has elucidated a great deal about hepatic physiology, Liver-directed gene therapy is on the threshold of human application. This research has been facilitated by excellent animal models and the advent of isolated hepatocyte transplantation. Relatively common conditions such as biliary atresia, however, remain largely unexplained and the viral hepatitides have no effective form of treatment. It remains a hope that our increase in knowledge in the fields of genetics and immunology will translate into advances in therapy. (C) 1999 Lippincott Williams & Wilkins, Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 23/09/20 alle ore 12:27:08