Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Treatment of idiopathic and postvaricocelectomy oligozoospermia with oral tamoxifen citrate
Autore:
Kadioglu, TC; Koksal, IT; Tunc, M; Nane, I; Tellaloglu, S;
Indirizzi:
Univ Istanbul, Fac Med, Dept Urol, Istanbul, Turkey Univ Istanbul Istanbul Turkey bul, Fac Med, Dept Urol, Istanbul, Turkey
Titolo Testata:
BJU INTERNATIONAL
fascicolo: 6, volume: 83, anno: 1999,
pagine: 646 - 648
SICI:
1464-4096(199904)83:6<646:TOIAPO>2.0.ZU;2-H
Fonte:
ISI
Lingua:
ENG
Soggetto:
OLIGOSPERMIA; MEN;
Keywords:
tamoxifen citrate; infertility; oligozoospermia; varicocelectomy;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
16
Recensione:
Indirizzi per estratti:
Indirizzo: Koksal, IT Serifkuyu Sokak Koksai Apt 33-6, TR-81170 Istanbul, Turkey Serifkuyu Sokak Koksai Apt 33-6 Istanbul Turkey TR-81170 rkey
Citazione:
T.C. Kadioglu et al., "Treatment of idiopathic and postvaricocelectomy oligozoospermia with oral tamoxifen citrate", BJU INT, 83(6), 1999, pp. 646-648

Abstract

Objective To identify a subgroup of men who may benefit from tamoxifen citrate (a widely prescribed drug for male infertility) among those with normogonadotrophic and hypergonadotrophic oligozoospermia, either idiopathic or after varicocelectomy. Patients and methods The study included infertile men with oligozoospermia, 136 referred to our outpatient clinic and 84 infertile after varicocelectomy. All patients received tamoxifen citrate (10 mg twice daily); semen analysis and hormone tests were repeated at the end of 3 and 6 months of treatment, the values being compared with those before treatment,Results The levels of follicle-stimulating hormone. luteinizing hormone and testosterone increased in all groups receiving tamoxifen citrate, Normogonadotrophic patients had a significant increase in sperm count and concentration, while the slight increase detected in the hypergonadotrophic group was statistically insignificant. Conclusion In patients with normogonadotrophic oligozoospermia, tamoxifen citrate may be offered as a practical and economic alternative before usingany assisted reproduction techniques, However. double-blind placebo-controlled trials are needed to confirm the findings of this preliminary study.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 20/09/20 alle ore 07:37:45