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Titolo:
Immunohistochemical expression of metallothionein in resected hepatic primary tumors and colorectal carcinoma metastases
Autore:
Stenram, U; Ohlsson, B; Tranberg, KG;
Indirizzi:
Univ Lund, Dept Pathol, Lund, Sweden Univ Lund Lund SwedenUniv Lund, Dept Pathol, Lund, Sweden Univ Lund, Dept Surg, Lund, Sweden Univ Lund Lund SwedenUniv Lund, Dept Surg, Lund, Sweden
Titolo Testata:
APMIS
fascicolo: 4, volume: 107, anno: 1999,
pagine: 420 - 424
SICI:
0903-4641(199904)107:4<420:IEOMIR>2.0.ZU;2-#
Fonte:
ISI
Lingua:
ENG
Soggetto:
LIVER; CISPLATIN; COPPER; CANCER;
Keywords:
metallothionein; immunohistochemistry; hepatic tumor; fibrolamellar carcinoma;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
17
Recensione:
Indirizzi per estratti:
Indirizzo: Stenram, U Univ Lund Hosp, Dept Pathol, S-22185 Lund, Sweden Univ Lund Hosp Lund Sweden S-22185 thol, S-22185 Lund, Sweden
Citazione:
U. Stenram et al., "Immunohistochemical expression of metallothionein in resected hepatic primary tumors and colorectal carcinoma metastases", APMIS, 107(4), 1999, pp. 420-424

Abstract

Metallothionein is a protein with affinity for metals and is present in several tumors. We examined its immunohistochemical expression in 37 resectedprimary liver tumors and 117 colorectal metastases. The reaction was intense in the two fibrolamellar hepatocellular carcinomas and in many of the hepatocytes of the pseudotumor case of focal nodular hyperplasia. The reaction was low or moderate in 5 of 17 ordinary hepatocellular carcinomas and in 4 of 14 cholangiocellular carcinomas. There was no reaction in one case each of spindle cell hepatocellular carcinoma, oncocytic adenoma and hemangioendothelial sarcoma. In the metastases, the reaction was low or moderate in 14 cases and negative in 103. Surrounding hepatocytes and stromal cells were more or less positive in all cases.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 13/07/20 alle ore 10:54:06