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Titolo:
Health-related quality of life (HRQOL), activity of daily living (ADL) anddepressive mood disorder in temporal lobe epilepsy patients
Autore:
Lehrner, J; Kalchmayr, R; Serles, W; Olbrich, A; Pataraia, E; Aull, S; Bacher, J; Leutmezer, F; Groppel, G; Deecke, L; Baumgartner, C;
Indirizzi:
Univ Vienna, Allgemeines Krankenhaus, Neurol Klin, A-1097 Vienna, Austria Univ Vienna Vienna Austria A-1097 s, Neurol Klin, A-1097 Vienna, Austria
Titolo Testata:
SEIZURE-EUROPEAN JOURNAL OF EPILEPSY
fascicolo: 2, volume: 8, anno: 1999,
pagine: 88 - 92
SICI:
1059-1311(199904)8:2<88:HQOL(A>2.0.ZU;2-2
Fonte:
ISI
Lingua:
ENG
Soggetto:
COMPLEX PARTIAL SEIZURES; OF-LIFE; PHENOMENOLOGY; LATERALITY; SYMPTOMS; PATTERNS; ANXIETY;
Keywords:
TLE; health-related quality of life; depressive mood disorder; pre-surgical evaluation;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
26
Recensione:
Indirizzi per estratti:
Indirizzo: Lehrner, J Univ-1097na, Allgemeines Krankenhaus, Neurol Klin, Wahringergurtel 18-20, A Univ Vienna Wahringergurtel 18-20 Vienna Austria A-1097 -20, A
Citazione:
J. Lehrner et al., "Health-related quality of life (HRQOL), activity of daily living (ADL) anddepressive mood disorder in temporal lobe epilepsy patients", SEIZURE-E J, 8(2), 1999, pp. 88-92

Abstract

We, determined the interrelations of chronological age, age at seizure onset, duration of seizure disorder, cognitive functioning (IQ), scales of activities of daily Living, depressive mood disorder and measures of health-related quality of life (HRQOL). Furthermore, we investigated the associationof the laterality of seizure onset zone and absence/presence of hippocampal atrophy and/or sclerosis (HA/HS) with measures of HRQOL, activities of daily living (ADL) and depressive mood disorder. In the setting of pre-surgical epilepsy evaluation, a sample of 56 patients with temporal lobe epilepsy(TLE) was studied using the Bonner Skalen fur Epilepsie (BPSE) and the depression inventory D-S of von Zerssen. Patients reported high levels of dependency on others and poor coping capabilities. Our data also showed specific ADL-behaviour suggesting social withdrawal and isolation. Our results indicate emotional impairment as a major problem in TLE, because 45% of our patients scored in the depressive range of the D-S depression scale. Depression score was found to be a powerful predictor of self-reported quality of life after adjusting for seizure-related variables, demographic variables and cognitive functioning (IQ). The only scale showing a significant laterality effect was ADL-home. No relationship between the dependent measures of HRQOL, ADL-social, ADL-cultural, depressive mood disorder and laterality of the epileptogenic zone or absence/presence of HA/HS was found. HRQOL and depressive mood disorder are strongly interrelated indicating that patients with depressive symptoms report lower quality of life and specific patterns of ADL. HRQOL, ADL and depressive mood disorder are largely independent of biological markers such as laterality of seizure onset zone and absence/presence of HA/HS in TLE.

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Documento generato il 17/09/19 alle ore 23:06:44