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Titolo:
Pituitary-adrenal and parasympathetic function in chronic schizophrenic patients with postoperative ileus or hypotension
Autore:
Kudoh, A; Ishihara, H; Matsuki, A;
Indirizzi:
Hirosaki Univ, Sch Med, Dept Anaesthesiol, Hirosaki, Aomori 036, Japan Hirosaki Univ Hirosaki Aomori Japan 036 siol, Hirosaki, Aomori 036, Japan
Titolo Testata:
NEUROPSYCHOBIOLOGY
fascicolo: 3, volume: 39, anno: 1999,
pagine: 125 - 130
SICI:
0302-282X(1999)39:3<125:PAPFIC>2.0.ZU;2-H
Fonte:
ISI
Lingua:
ENG
Soggetto:
SURGICAL STRESS; EXCRETION; HEART;
Keywords:
pituitary-adrenal function; parasympathetic function; schizophrenia chronic; ileus, postoperative; hypotension;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
24
Recensione:
Indirizzi per estratti:
Indirizzo: Kudoh, A Hirosaki Univ, Sch Med, Dept Anaesthesiol, Hirosaki, Aomori 036, Japan Hirosaki Univ Hirosaki Aomori Japan 036 osaki, Aomori 036, Japan
Citazione:
A. Kudoh et al., "Pituitary-adrenal and parasympathetic function in chronic schizophrenic patients with postoperative ileus or hypotension", NEUROPSYCHB, 39(3), 1999, pp. 125-130

Abstract

We studied the relationship between parasympathetic, sympathetic and pituitary-adrenal functions in chronic schizophrenic patients with complicationssuch as postoperative paralytic ileus and hypotension during anaesthesia. Plasma epinephrine, norepinephrine (NE), adrenocorticotropin (ACTH), cortisol and the coefficient of variation (CV) of the R-R intervals on the electrocardiogram (ECG) as parasympathetic parameter were measured in schizophrenic and control patients. The CV value of the R-R interval on the ECG beforethe start of anaesthesia was significantly decreased to 2.3 +/- 0.2 in theschizophrenic patients as compared with 3.5 +/- 0.3 of the control patients. The CV value of the R-R interval on the ECG in schizophrenic patients with postoperative paralytic ileus was more diminished to 1.6 +/- 0.2. The CVvalues in schizophrenic patients with and without hypotension during anaesthesia were similar and we could not find any significant difference. Chronic schizophrenic patients developed a decrease in NE, ACTH and cortisol responses to surgical stress, while there were no significant differences in these hormonal changes between those patients with and without paralytic ileus and hypotension during anaesthesia. In conclusion, the CV value of the ECG R-R interval may be correlated inversely with the expectancy of postoperative ileus in chronic schizophrenic patients. Their suppressed pituitary-adrenal function and sym pathetic system may be indirectly associated with the paralytic ileus and hypotension.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 03/04/20 alle ore 03:05:47