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Titolo:
Experimental psychosis research with hallucinogenic drugs past and present
Autore:
Gouzoulis-Mayfrank, E;
Indirizzi:
Rheinachen,al TH Aachen, Fak Med, Klin Psychiat & Psychotherapie, D-52074 A Rhein Westfal TH Aachen Aachen Germany D-52074 Psychotherapie, D-52074 A
Titolo Testata:
NERVENHEILKUNDE
fascicolo: 2, volume: 18, anno: 1999,
pagine: 84 - 92
SICI:
0722-1541(199903)18:2<84:EPRWHD>2.0.ZU;2-H
Fonte:
ISI
Lingua:
GER
Soggetto:
POSITRON EMISSION TOMOGRAPHY; DISORDERED SCHIZOPHRENIC-PATIENTS; HEALTHY-VOLUNTEERS; BLOOD-FLOW; METABOLIC HYPERFRONTALITY; GLUCOSE-UTILIZATION; STARTLE REFLEX; HUMAN-BRAIN; KETAMINE; MODEL;
Keywords:
model psychosis; experimental psychosis; hallucinogens;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
95
Recensione:
Indirizzi per estratti:
Indirizzo: Gouzoulis-Mayfrank, E RheinrWestfal TH Aachen, Fak Med, Klin Psychiat & Psychotherapie, Pauwelsst Rhein Westfal TH Aachen Pauwelsstr 30 Aachen Germany D-52074
Citazione:
E. Gouzoulis-Mayfrank, "Experimental psychosis research with hallucinogenic drugs past and present", NERVENHEILK, 18(2), 1999, pp. 84-92

Abstract

Systematic human experimental research with hallucinogenic drugs has a long tradition. Scientific interest in this field faded at the end of the 60ies, but is currently again on the rise; Hallucinogenic drug induced states share many phenomenological features with early and acute productive stages of endogenous schizophrenic and schizophrenia-spectrum psychoses. Therefore, they can be considered as "models" for these particular stages of the disorders. During the last decades, knowledge about the interactions of psychoactive drugs with the endogenous transmitter systems has accumulated and new modern techniques for the study of brain function have become available. Current research with "model psychoses" has the potential to identify linking variables between psycho(patho)logical conditions and neurobiological alterations involved in both pharmacologically induced and naturally occurring acute psychotic states. Hence, the hallucinogen induced "model psychoses"represent useful tools for syndrome-oriented research into the neurobiological mechanisms involved in psychotic disorders. The present article summarizes historical and current aspects of the research with experimental psychoses.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 21/01/20 alle ore 00:55:35