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Titolo:
Long-term followup of the North American multicenter UroLume* trial for the treatment of external detrusor-sphincter dyssynergia
Autore:
Chancellor, MB; Gajewski, J; Ackman, CFD; Appell, RA; Bennett, J; Binard, J; Boone, TB; Chetner, MP; Crewalk, JA; Defalco, A; Foote, J; Green, B; Juma, S; Jung, SY; Linsenmeyer, TA; MacMillan, R; Mayo, M; Ozawa, H; Roehrborn, CG; Shenot, PJ; Stone, A; Vazquez, A; Killorin, W; Rivas, DA;
Indirizzi:
Univ Pittsburgh, Sch Med, Pittsburgh, PA 15261 USA Univ Pittsburgh Pittsburgh PA USA 15261 Sch Med, Pittsburgh, PA 15261 USA Thomas Jefferson Univ, Philadelphia, PA 19107 USA Thomas Jefferson Univ Philadelphia PA USA 19107 hiladelphia, PA 19107 USA Montreal Gen Hosp, Montreal, PQ H3G 1A4, Canada Montreal Gen Hosp Montreal PQ Canada H3G 1A4 Montreal, PQ H3G 1A4, Canada Misericordia Hosp, Edmonton, AB, Canada Misericordia Hosp Edmonton AB Canada ricordia Hosp, Edmonton, AB, Canada New Halifax Infirm, Halifax, NS, Canada New Halifax Infirm Halifax NS Canada Halifax Infirm, Halifax, NS, Canada E Toronto Gen Hosp, Toronto, ON, Canada E Toronto Gen Hosp Toronto ON Canada ronto Gen Hosp, Toronto, ON, Canada Louisiana State Univ, Med Ctr, New Orleans, LA 70112 USA Louisiana State Univ New Orleans LA USA 70112 , New Orleans, LA 70112 USA Shepherd Spinal Ctr, Atlanta, GA USA Shepherd Spinal Ctr Atlanta GA USAShepherd Spinal Ctr, Atlanta, GA USA Univ Calif San Diego, Vet Affairs Med Ctr, San Diego, CA 92161 USA Univ Calif San Diego San Diego CA USA 92161 Ctr, San Diego, CA 92161 USA Univ Calif Davis, Davis, CA 95616 USA Univ Calif Davis Davis CA USA 95616Univ Calif Davis, Davis, CA 95616 USA Dallas Vet Affairs Med Ctr, Dallas, TX 75216 USA Dallas Vet Affairs Med Ctr Dallas TX USA 75216 Ctr, Dallas, TX 75216 USA Univ Washington, Seattle, WA 98195 USA Univ Washington Seattle WA USA 98195 iv Washington, Seattle, WA 98195 USA Kessler Inst Rehabil, W Orange, NJ USA Kessler Inst Rehabil W Orange NJ USA sler Inst Rehabil, W Orange, NJ USA Univ Puerto Rico, San Juan, PR 00936 USA Univ Puerto Rico San Juan PR USA00936 uerto Rico, San Juan, PR 00936 USA Univ S Florida, Vet Affairs Med Ctr, Tampa, FL 33612 USA Univ S Florida Tampa FL USA 33612 et Affairs Med Ctr, Tampa, FL 33612 USA
Titolo Testata:
JOURNAL OF UROLOGY
fascicolo: 5, volume: 161, anno: 1999,
pagine: 1545 - 1550
SICI:
0022-5347(199905)161:5<1545:LFOTNA>2.0.ZU;2-P
Fonte:
ISI
Lingua:
ENG
Soggetto:
SPINAL-CORD INJURY; URINARY SPHINCTER; URETHRAL STENTS; BLADDER; PROSTHESIS; STRICTURES; WALLSTENT; NEODYMIUM; ABLATION; LESIONS;
Keywords:
stents; spinal cord injuries; urodynamics; urinary incontinence; urinary tract infections;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
41
Recensione:
Indirizzi per estratti:
Indirizzo: Chancellor, MB Suite 700,Kaufmann Bldg,3471 5th Ave, Pittsburgh, PA 15213 USA Suite 700,Kaufmann Bldg,3471 5th Ave Pittsburgh PA USA 15213
Citazione:
M.B. Chancellor et al., "Long-term followup of the North American multicenter UroLume* trial for the treatment of external detrusor-sphincter dyssynergia", J UROL, 161(5), 1999, pp. 1545-1550

Abstract

Purpose: We determine the long-term efficacy and safety of the UroLume stent as minimally invasive treatment for external detrusor-sphincter dyssynergia in spinal cord injured men. Materials and Methods: A total of 160 spinal cord injured men with a mean age plus or minus standard deviation of 36.3 +/- 12.1 years (range 16 to 74) were prospectively treated with an endoprosthesis at 15 centers as part of the North American UroLume trial for external detrusor-sphincter dyssynergia. Urodynamic parameters, including voiding pressure, residual urine volume and bladder capacity, were compared before treatment and at 1, 2, 3, 4 and 5 years after treatment. Results: Mean voiding pressure was 75.1 +/- 28.2 cm. water before treatment in the 160 patients, and 37.4 +/- 23.9 at year 1 in 97, 39.5 +/- 22.2 at year 2 in 84, 42.6 +/- 27.3 at year 3 in 61, 46.3 +/- 33.2 at year 4 in 57 and 44.2 +/- 28.9 cm. at year 5 in 41 after stent insertion (p < 0.001). Residual urine volume decreased after stent placement and was maintained throughout the 5-year followup (p < 0.001). Mean cystometric capacity remained constant from 269 +/- 1.55 before insertion to 337 +/- 182 mi. 5 years later (p = 0.17). HydRronephrosis and autonomic dysreflexia improved or stabilized in most patients with functioning stents. Stent explant was necessary in 24 patients (15%), of whom 4 (16.7%) had another stent implanted. Conclusions: The UroLume stent demonstrates long-term safety and efficacy for the treatment of external detrusor-sphincter dyssynergia. The outcome was similar in men with and without previous sphincterotomy.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 20/09/20 alle ore 07:04:47