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Titolo:
Aggressive giant pituitary adenoma presenting as a nasopharyngeal mass: magnetic resonance imaging and pathologic findings
Autore:
Ravichandran, TP; Bakshi, R; Heffner, RR; Gibbons, KJ; Bates, VE; Durante, DJ; Kinkel, WR;
Indirizzi:
SUNYmaginglo, Millard Fillmore Hlth Syst, Sch Med & Biomed Sci, Lucy Dent I SUNY Buffalo Buffalo NY USA 14209 Syst, Sch Med & Biomed Sci, Lucy Dent I SUNY Buffalo, Millard Fillmore Hlth Syst, Sch Med & Biomed Sci, Dent Neurol SUNY Buffalo Buffalo NY USA 14209 Syst, Sch Med & Biomed Sci, Dent Neurol SUNY,Buffalo, Millard Fillmore Hlth Syst, Sch Med & Biomed Sci, Dept Pathol SUNY Buffalo Buffalo NY USA 14209 Syst, Sch Med & Biomed Sci, Dept Pathol SUNYurg,falo, Millard Fillmore Hlth Syst, Sch Med & Biomed Sci, Dept Neuros SUNY Buffalo Buffalo NY USA 14209 Syst, Sch Med & Biomed Sci, Dept Neuros SUNYuffalo,o, Millard Fillmore Hlth Syst, Sch Med & Biomed Sci, Dept Med, B SUNY Buffalo Buffalo NY USA 14209 Syst, Sch Med & Biomed Sci, Dept Med, B
Titolo Testata:
JOURNAL OF NEURO-ONCOLOGY
fascicolo: 1, volume: 41, anno: 1999,
pagine: 71 - 75
SICI:
0167-594X(199901)41:1<71:AGPAPA>2.0.ZU;2-N
Fonte:
ISI
Lingua:
ENG
Soggetto:
CARCINOMA; SPREAD; TUMOR; CT;
Keywords:
pituitary adenoma; neoplasm; macroadenoma; MRI; nasopharynx;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
15
Recensione:
Indirizzi per estratti:
Indirizzo: Bakshi, R SUNYmaginglo, Millard Fillmore Hlth Syst, Sch Med & Biomed Sci, Lucy Dent I SUNY Buffalo 3 Gates Circle Buffalo NY USA 14209 ci, Lucy Dent I
Citazione:
T.P. Ravichandran et al., "Aggressive giant pituitary adenoma presenting as a nasopharyngeal mass: magnetic resonance imaging and pathologic findings", J NEURO-ONC, 41(1), 1999, pp. 71-75

Abstract

We report a giant pituitary adenoma with aggressive histologic features that prominently invaded the nasopharynx. Magnetic resonance imaging (MRI) demonstrated a large heterogeneous nodular mass that was hypointense to isointense on T1-weighted images and mixed hypointense, isointense, and hyperintense on T2-weighted images. The mass measured 7.5 x 5 x 7 cm, extending from the nasopharynx posteriorly through the clivus, and superiorly through the paranasal sinuses, and sellar-suprasellar region. After contrast administration, heterogeneous nodular enhancement was noted. A nasopharyngeal neoplasm extending into the sella was suspected because voice change and nasal speech long preceded the patient's visual symptoms. A biopsy disclosed an aggressive, infiltrating, hemorrhagic tumor, which was diagnosed as a non-secreting pituitary macroadenoma. This report indicates that pituitary adenomas may grow invasively to tremendously large sizes resulting in their initial presentation as nasopharyngeal masses.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 07/07/20 alle ore 22:05:22