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Titolo:
Genetic factors involved in cardiac calcification in STS/A and DBA/2 mouseinbred strains
Autore:
Van den Broek, FAR; Van Lith, HA; Van Zutphen, LFM;
Indirizzi:
Agr Univ Wageningen, NL-6700 EV Wageningen, Netherlands Agr Univ Wageningen Wageningen Netherlands NL-6700 EV ingen, Netherlands Univdstrecht, Fac Vet Med, Dept Lab Anim Sci, NL-3508 TC Utrecht, Netherlan Univ Utrecht Utrecht Netherlands NL-3508 TC L-3508 TC Utrecht, Netherlan
Titolo Testata:
JOURNAL OF EXPERIMENTAL ANIMAL SCIENCE
fascicolo: 4, volume: 39, anno: 1999,
pagine: 115 - 121
SICI:
0939-8600(199903)39:4<115:GFIICC>2.0.ZU;2-Q
Fonte:
ISI
Lingua:
ENG
Soggetto:
RECOMBINANT CONGENIC STRAINS; MICE; LESIONS; CALCINOSIS; TOOL;
Keywords:
DBA/2 mice; dystrophic cardiac calcification; genetics; Dyscalc; recombinant inbred strains;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Agriculture,Biology & Environmental Sciences
Citazioni:
15
Recensione:
Indirizzi per estratti:
Indirizzo: Van den Broek, FAR AgrrlandsWageningen, Smal Anim Facil,POB 8129, NL-6700 EV Wageningen, Nethe Agr Univ Wageningen Smal Anim Facil,POB 8129 Wageningen Netherlands NL-6700 EV
Citazione:
F.A.R. Van den Broek et al., "Genetic factors involved in cardiac calcification in STS/A and DBA/2 mouseinbred strains", J EXP ANIM, 39(4), 1999, pp. 115-121

Abstract

The occurrence of juvenile dystrophic cardiac calcification (DCC) has beenstudied in an F2-intercross and backcross of DBA/2Ola and BALB/cOlaHsd mice and in CcS/Dem recombinant congenic strains (RCS) and their STS/A and BALB/cHeA parents. From the results of the F2-intercross and backcross it could be concluded that two to four genes are involved in the DCC susceptibility of the DBA/2Ola strain. Screening of the CcS recombinant congenic strainsindicated that at least one of these genes is located on the proximal end of Chromosome 7. This is in line with the results of IVANDIC et al. (1996) who have previously found evidence for a major gene (Dyscalc) on Chromosome7.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 27/05/20 alle ore 09:28:53