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Titolo:
Morphological effects on in-stent restenosis assessed by intravascular ultrasound imaging
Autore:
Yamaguchi, T; Hamasaki, S; Arima, S; Biro, S; Kihara, K; Fukumoto, N; Kamekou, M; Nakano, F; Yoshitama, T; Kiyonaga, K; Nakjima, H; Nakao, S; Tei, C;
Indirizzi:
Kagoshima Univ, Fac Med, Dept Internal Med 1, Kagoshima 8908520, Japan Kagoshima Univ Kagoshima Japan 8908520 l Med 1, Kagoshima 8908520, Japan
Titolo Testata:
JAPANESE HEART JOURNAL
fascicolo: 2, volume: 40, anno: 1999,
pagine: 109 - 118
SICI:
0021-4868(199903)40:2<109:MEOIRA>2.0.ZU;2-E
Fonte:
ISI
Lingua:
ENG
Soggetto:
LUMINAL CORONARY ANGIOPLASTY; BALLOON-EXPANDABLE-STENT; INTRACORONARY STENTS; ARTERY DISEASE; MODEL; PROLIFERATION; IMPLANTATION; MECHANISMS; PLACEMENT; RABBIT;
Keywords:
intravascular ultrasound; stent implantation; coronary restenosis;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
22
Recensione:
Indirizzi per estratti:
Indirizzo: Hamasaki, S Kagoshima Univ, Fac Med, Dept Internal Med 1, 8-35-1 Sakuragaoka, Kagoshima Kagoshima Univ 8-35-1 Sakuragaoka Kagoshima Japan 8908520 ima
Citazione:
T. Yamaguchi et al., "Morphological effects on in-stent restenosis assessed by intravascular ultrasound imaging", JPN HEART J, 40(2), 1999, pp. 109-118

Abstract

The purpose of this study was to evaluate the rupture and dissection of the vessel wall immediately after balloon dilatation by intravascular ultrasound (IVUS) imaging and to predict restenosis in patients who underwent subsequent coronary stent implantation. Stent implantation improves the long-term results of coronary angioplasty by reducing lesion elastic recoil and arterial remodeling. However, severalstudies have suggested that neointimal hyperplasia is the cause of in-stent restenosis. We recruited 60 patients in whom IVUS studies were performed immediately after successful balloon dilatation and just before stent implantation. We compared IVUS parameters with 6-month follow-up quantitative coronary angiography. This was performed in 51 lesions of 51 patients (85%). Qualitative analysis included assessment of plaque composition, plaque eccentricity, plaque fracture and the presence of dissection. In addition, minimal luminal diameter, percent diameter stenosis, percent area stenosis and plaque burdenwere quantitatively analyzed. Two morphological patterns after balloon dilatation were classified by IVUS. Type I was defined as absence or partial tear of the plaque without disclosure of the media to lumen (22 lesions). Type II was defined as a split in the plaque or dissection of the vessel wall with disclosure of the media to the lumen (29 lesions). At 6 months follow-up, angiographic restenosis occurred in 17 of the 51 lesions (33%). Restenosis was significantly (p < 0.05) more likely to occur in type II (13/29: 45% incidence) than in type I (4/22: 18% incidence). The assessment of plaque morphology immediately after balloon dilatation and before stent implantation provides important therapeutic and prognostic implications.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 22/09/20 alle ore 09:04:45