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Titolo:
Exposure to an abundance of cat (Fel d 1) and dog (Can f 1) allergens in Swedish farming households
Autore:
Parvaneh, S; Kronqvist, M; Johansson, E; van Hage-Hamsten, M;
Indirizzi:
Karolinska Hosp & Inst, Dept Lab Med, Div Clin Immunol, Stockholm, Sweden Karolinska Hosp & Inst Stockholm Sweden Clin Immunol, Stockholm, Sweden Danderyd Hosp, Dept Med, S-18288 Danderyd, Sweden Danderyd Hosp DanderydSweden S-18288 Dept Med, S-18288 Danderyd, Sweden
Titolo Testata:
ALLERGY
fascicolo: 3, volume: 54, anno: 1999,
pagine: 229 - 234
SICI:
0105-4538(199903)54:3<229:ETAAOC>2.0.ZU;2-X
Fonte:
ISI
Lingua:
ENG
Soggetto:
INDOOR ALLERGENS; DUST-MITE; RISK-FACTORS; D-I; ASTHMA; SENSITIZATION; CHILDREN; HOMES; POPULATION; BUILDINGS;
Keywords:
Can f 1; cat allergen; dog allergen; exposure; farmers; Fel d 1; sensitization;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
26
Recensione:
Indirizzi per estratti:
Indirizzo: Parvaneh, S Karolinska Hosp, Div Clin Immunol, S-17176 Stockholm, Sweden Karolinska Hosp Stockholm Sweden S-17176 6 Stockholm, Sweden
Citazione:
S. Parvaneh et al., "Exposure to an abundance of cat (Fel d 1) and dog (Can f 1) allergens in Swedish farming households", ALLERGY, 54(3), 1999, pp. 229-234

Abstract

Background: Earlier studies have shown that farmers are to a low degree sensitized to animal allergens. We have measured the amount of cat (Fel d 1) and dog (Can f 1) in farm households and examined the relationship between exposure and sensitization to cat and dog allergens. Methods: Dust samples from the homes of 403 farmers who had participated in an epidemiologic follow-up study on respiratory symptoms were analyzed for allergen content by two-site ELISA methods. Results: Fel d 1 was detected in 99.5% of the farmers' households ranging from 0.055 to 1455 mu g/g dust in mattresses (GM 13.2) and to 3775 mu g/g dust in living-room carpets (GM 17.1). Can f 1 was detected in 90.6% of the households from 0.2 to 116 mu g/g dust in mattresses (CM 2.0) and to 504 mug/g dust in carpets (GM 4.3). Homes with pets present had the highest levels of the allergens (P<0.001). A total of 8.4% and 7.4% of the farmers weresensitized to cat and dog, respectively. A significant correlation was noted between exposure to the allergens and specific IgE to cat and dog, respectively (P<0.001). Sensitization to cat (OR=4.9) and dog (OR=17.8) was significantly associated with asthma. Conclusions: In spite of the abundance of Fel d 1 and Can f 1, farmers areonly to a low degree sensitized to cats and dogs.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 28/09/20 alle ore 05:41:38