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Titolo:
DIFFERENCES IN THE ERYTHROCYTE AGGREGATION LEVEL BETWEEN VEINS AND ARTERIES OF NORMOLIPIDEMIC AND HYPERLIPIDEMIC INDIVIDUALS
Autore:
CLOUTIER G; WENG XD; ROEDERER GO; ALLARD L; TARDIF F; BEAULIEU R;
Indirizzi:
INST RECH CLIN MONTREAL,BIOMED ENGN LAB,110 AVE PINS OUEST MONTREAL PQ H2W 1R7 CANADA INST RECH CLIN MONTREAL,LAB HYPERLIPIDEMIA & ATHEROSCLEROSIS MONTREALPQ H2W 1R7 CANADA INST RECH CLIN MONTREAL,SERV ECHODOPPLER MONTREAL PQ H2W 1R7 CANADA MONTREAL GEN HOSP,HOTEL DIEU,DIV ONCOL & HEMATOL MONTREAL PQ H3G 1A4 CANADA
Titolo Testata:
Ultrasound in medicine & biology
fascicolo: 9, volume: 23, anno: 1997,
pagine: 1383 - 1393
SICI:
0301-5629(1997)23:9<1383:DITEAL>2.0.ZU;2-C
Fonte:
ISI
Lingua:
ENG
Soggetto:
SPONTANEOUS ECHO CONTRAST; MITRAL-VALVE DISEASE; SPONTANEOUS ECHOCARDIOGRAPHIC CONTRAST; SMOKE-LIKE ECHO; DOPPLER ULTRASOUND; SHEAR RATE; TRANSESOPHAGEAL ECHOCARDIOGRAPHY; CEREBROVASCULAR-DISEASE; DILATED CARDIOMYOPATHY; PLATELET-AGGREGATION;
Keywords:
SPONTANEOUS ECHO CONTRAST; ACOUSTIC BACKSCATTERING; RED CELL AGGREGATION; POWER DOPPLER ULTRASOUND; HYPERLIPIDEMIA; BLOOD FLOW; HEMODYNAMICS; BIORHEOLOGY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
39
Recensione:
Indirizzi per estratti:
Citazione:
G. Cloutier et al., "DIFFERENCES IN THE ERYTHROCYTE AGGREGATION LEVEL BETWEEN VEINS AND ARTERIES OF NORMOLIPIDEMIC AND HYPERLIPIDEMIC INDIVIDUALS", Ultrasound in medicine & biology, 23(9), 1997, pp. 1383-1393

Abstract

The objectives of this study were to detect differences in the Doppler power backscattered by blood in vivo, and to identify factors affecting the backscattered power, The main hypothesis was that variations in the erythrocyte aggregation level between veins and arteries of normolipidemic and hyperlipidemic individuals can be detected with power Doppler ultrasound, Doppler measurements were performed at 5 MHz, with an Acuson 128 XP/10 system, over the carotid artery and jugular vein, external iliac artery and vein, common femoral artery and vein and popliteal artery and vein, Doppler signals were recorded at the center ofeach vessel to optimize the detection of erythrocyte aggregation, andprocessed off-line to obtain the backscattered power, The power of each recording was compensated for Doppler gain differences, tissue attenuation,vith depth and transmitted po,ver variations occurring with pulse-repetition interval modifications, Results showed statistically stronger backscattered power in veins compared to arteries for the iliac, femoral and popliteal sites, In comparison with healthy subjects, stronger powers were observed in hyperlipidemic patients for the femoraland popliteal sites, Power differences were also found between peripheral measurements, On the other hand, no difference was observed between the power measured in the carotid artery and jugular vein for both groups of individuals, Multiple linear regression analyses were performed to identify factors affecting the backscattered power, Results showed a correlation (r) of 71.2% between the Doppler power in the femoral vein and the linear combination of two parameters: an erythrocyte aggregation index S-10 measured with a laser scattering method, and the diameter of the vessel measured on B-mode images. Statistically significant linear correlation levels were also found between S-10 and the Doppler power in various vessels, In conclusion, this study showed thatpower Doppler differences exist in vivo in large vessels between veins and arteries of normolipidemic and hyperlipidemic individuals. The Doppler power variations were also shown to be related to erythrocyte aggregation. (C) 1997 World Federation for Ultrasound in Medicine & Biology.

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Documento generato il 29/11/20 alle ore 16:28:42