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Titolo:
ANANDAMIDE MODULATES SLEEP AND MEMORY IN RATS
Autore:
MURILLORODRIGUEZ E; SANCHEZALAVEZ M; NAVARRO L; MARTINEZGONZALEZ D; DRUCKERCOLIN R; PROSPEROGARCIA O;
Indirizzi:
UNIV NACL AUTONOMA MEXICO,FAC MED,DEPT FISIOL,GRP NEUROCIENCIAS,APDO POSTAL 70-250 MEXICO CITY 04510 DF MEXICO UNIV NACL AUTONOMA MEXICO,FAC MED,DEPT FISIOL,GRP NEUROCIENCIAS MEXICO CITY 04510 DF MEXICO UNIV NACL AUTONOMA MEXICO,INST FISIOL CELULAR,DEPT NEUROCIENCIAS MEXICO CITY 04510 DF MEXICO
Titolo Testata:
Brain research
fascicolo: 1-2, volume: 812, anno: 1998,
pagine: 270 - 274
SICI:
0006-8993(1998)812:1-2<270:AMSAMI>2.0.ZU;2-B
Fonte:
ISI
Lingua:
ENG
Soggetto:
PASSIVE-AVOIDANCE TASK; CANNABINOID RECEPTOR; ARACHIDONIC-ACID; MOLECULAR CHARACTERIZATION; BRAIN CONSTITUENT; PRODUCE AMNESIA; CHICK; CEREBRODIENE; MECHANISMS; INHIBITORS;
Keywords:
ARACHIDONIC ACID; RAPID-EYE MOVEMENT (REM) SLEEP; PAIN; LOCOMOTOR ACTIVITY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
31
Recensione:
Indirizzi per estratti:
Citazione:
E. Murillorodriguez et al., "ANANDAMIDE MODULATES SLEEP AND MEMORY IN RATS", Brain research, 812(1-2), 1998, pp. 270-274

Abstract

In this study we have assessed the effect of the intracerebroventricular administration of anandamide (ANA) as well as its precursor metabolite arachidonic acid (AA), on the sleep-wakefulness cycle, memory formation, locomotor activity and pain perception. Our results have indicated that ANA strikingly increases slow-wave sleep (SWS)2 and rapid-eye movement (REM) sleep at the expense of wakefulness (W); while deteriorating memory consolidation. ANA also increases locomotor activity but does not modify pain perception threshold. In contrast, AA increasesW and reduces SWS2, while deteriorating memory consolidation and increasing locomotor activity. AA has no effect on pain perception. These results suggest that the brain cannabinoid system participates in the modulation of the vigilance states and mnemonic processes. Additionally, they suggest that the effect on pain perception may be a peripheralrather than a central effect. (C) 1998 Elsevier Science B.V. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/03/20 alle ore 15:43:13