Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
EFFECTS OF HEMATOMA ON THE SHORT-TERM FATE OF EXPERIMENTAL MICROVENOUS AUTOGRAFTS
Autore:
BAYRAMICLI M; YILMAZ B; SAN T; NUMANOGLU A;
Indirizzi:
INST CRANIOFACIAL & RECONSTRUCT SURG,3RD FLOOR,FISHER CTR,16001 W 9 MILE RD SOUTHFIELD MI 48075 MARMARA UNIV,SCH MED,DEPT PLAST & RECONSTRUCT SURG ISTANBUL TURKEY MARMARA UNIV,SCH MED,ELECTRON MICROSCOPY UNIT ISTANBUL TURKEY
Titolo Testata:
Journal of reconstructive microsurgery
fascicolo: 8, volume: 14, anno: 1998,
pagine: 575 - 586
SICI:
0743-684X(1998)14:8<575:EOHOTS>2.0.ZU;2-9
Fonte:
ISI
Lingua:
ENG
Soggetto:
AUTOGENOUS VEIN GRAFTS; THROMBUS FORMATION; MICROVASCULAR ANASTOMOSES; ARTERIAL SUBSTITUTES; INTIMAL HYPERPLASIA; SMALL VESSELS; RAT; MODEL; ENDOTHELIALIZATION; ENDOTHELIUM;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
54
Recensione:
Indirizzi per estratti:
Citazione:
M. Bayramicli et al., "EFFECTS OF HEMATOMA ON THE SHORT-TERM FATE OF EXPERIMENTAL MICROVENOUS AUTOGRAFTS", Journal of reconstructive microsurgery, 14(8), 1998, pp. 575-586

Abstract

The early effects of hematoma on the healing pattern of interpositional vein grafts were studied in 60 rats. In all animals, vein grafts approximately 10-mm in length were used to bridge defects created in thefemoral artery and vein on the same side, with a 1:1 graft-to-host diameter match. Grafted vessels were completely covered with hematoma and separated from the surrounding tissue in 30 animals, while the other30 rats served as controls. Both groups were divided into six subgroups of five animals each, according to the age of the grafts: 1, 3, 5, 7, 14, and 21 days. Graft patency and healing were assessed both clinically and histologically. 20/30 (66.6 percent) of the interarterial and 27/30 (90 percent) of the intervenous vein grafts in Group 1 (hematoma group), and 28/30 (93.3 percent) of the interarterial and 29/30 (96.6 percent) of the intervenous vein grafts in Group 2 (controls) were found patent. The patency rate of the interarterial vein grafts in thehematoma group was statistically significantly lower than in the control group and than in the intervenous vein grafts of the same group (p<0.005). The majority of interarterial vein-graft failures occurred after postoperative day 7 in Group 1. Patent specimens were examined under scanning electron and light microscopy. The authors concluded that perivascular hematoma caused spasm and flow disturbance, prolonged vessel-wall ischemia, and severe vessel-wall injury in the arterial circulation of the microvenous grafts. It also delayed the healing process and subjected the grafts to the development of occlusive mural thrombus. In contrast, the healing pattern of the intervenous vein grafts wasnot markedly influenced by perivascular hematoma, and equilibrium between thrombogenic and antithrombogenic factors on the graft surface was restored over a short period of time.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/11/20 alle ore 00:36:43