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Titolo:
AUTOMATIC SYSTEM FOR THE ASSAY OF GUANIDINO COMPOUNDS TO ASSESS UREMIC STATUS AND EFFECT OF HEMODIALYSIS
Autore:
NOHARA Y; HANAI T; SUZUKI J; MATSUMOTO G; IINUMA F; KUBO H; KINOSHITA T;
Indirizzi:
KEIO UNIV,SCH PHARMACEUT SCI,MINATO KU,9-1 SHIROKANE 5 TOKYO 108 JAPAN INST PASTEUR,HLTH RES FDN,INST TECHNOL ANAL,SAKYO KU KYOTO 606 JAPAN MATSUMOTO HOSP,DEPT MED CHICHIBU SAITAMA 368 JAPAN TEIKYO UNIV,SCH PHARMACEUT SCI SAGAMIKO KANAGAWA 19901 JAPAN
Titolo Testata:
Chemical and Pharmaceutical Bulletin
fascicolo: 11, volume: 46, anno: 1998,
pagine: 1844 - 1845
SICI:
0009-2363(1998)46:11<1844:ASFTAO>2.0.ZU;2-P
Fonte:
ISI
Lingua:
ENG
Soggetto:
PERFORMANCE LIQUID-CHROMATOGRAPHY; POST-COLUMN DERIVATIZATION; NINHYDRIN;
Keywords:
GUANIDINOSUCCINIC ACID; METHYLGUANIDINE; HEMODIALYSIS; HPLC; UREMIA; ANURIA; AUTOMATED ANALYSIS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
6
Recensione:
Indirizzi per estratti:
Citazione:
Y. Nohara et al., "AUTOMATIC SYSTEM FOR THE ASSAY OF GUANIDINO COMPOUNDS TO ASSESS UREMIC STATUS AND EFFECT OF HEMODIALYSIS", Chemical and Pharmaceutical Bulletin, 46(11), 1998, pp. 1844-1845

Abstract

An automated HPLC system coupled with fluorometry Has established forthe sensitive, rapid, and accurate assay of serum guanidines. Naturally fluorescent materials characteristic of the sera of uremic patients(uremic fluorescences) which interfere with the assay were removed simultaneously with deproteinization, Application of this method revealed that the uremic patients who are capable of excreting: urine under hemodialysis therapy show low serum guanidinosuccinic acid levels. The interval between hemodialysis sessions in one of these patients was prolonged while monitoring guanidinosuccinic acid level using the present method without any hazardous effect.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/03/20 alle ore 08:49:17