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Titolo:
CLONIDINE USE AND ABUSE AMONG METHADONE PROGRAM APPLICANTS AND PATIENTS
Autore:
BEUGER M; TOMMASELLO A; SCHWARTZ R; CLINTON M;
Indirizzi:
UNIV MARYLAND,SCH PHARM,OFF SUBST ABUSE STUDIES,CENTURY BLDG,ROOM 314,516 W FAYETTE ST BALTIMORE MD 21201 UNIV MARYLAND,SCH PHARM,OFF SUBST ABUSE STUDIES BALTIMORE MD 21201 UNIV MARYLAND,DIV ALCOHOL & DRUG ABUSE,DEPT PSYCHIAT COLLEGE PK MD 20742
Titolo Testata:
Journal of substance abuse treatment
fascicolo: 6, volume: 15, anno: 1998,
pagine: 589 - 593
SICI:
0740-5472(1998)15:6<589:CUAAAM>2.0.ZU;2-0
Fonte:
ISI
Lingua:
ENG
Soggetto:
ALCOHOL WITHDRAWAL; MAINTENANCE; DETOXIFICATION; DEPENDENCE; SMOKING;
Keywords:
CLONIDINE ABUSE; OPIOID SUBSTITUTION TREATMENT; METHADONE; PRESCRIPTION DRUG ABUSE; SUBSTANCE ABUSE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Physical, Chemical & Earth Sciences
Physical, Chemical & Earth Sciences
Citazioni:
30
Recensione:
Indirizzi per estratti:
Citazione:
M. Beuger et al., "CLONIDINE USE AND ABUSE AMONG METHADONE PROGRAM APPLICANTS AND PATIENTS", Journal of substance abuse treatment, 15(6), 1998, pp. 589-593

Abstract

Forty-eight consecutive applicants and 30 known clonidine-abusing methadone patients at three methadone treatment programs were surveyed regarding their use of clonidine. Two distinct patterns of clonidine useemerged. Of 22 applicants who took clonidine illicitly, 15 used it primarily to decrease opioid withdrawal, as well as for its sedating effect. Applicants mostly obtained it from physicians, used an average dose of 0.37 mg at a time, and about one third believed clonidine to be addictive. In contrast, clonidine-using patients took clonidine primarily for its psychoactive effects, including the interaction with methadone, in addition to decreasing opioid withdrawal. Patients obtained clonidine frequently on the street and from family or friends, but lessfrom physicians. The average reported dose for patients was 0.6 mg. The vast majority of these patients felt clonidine was addictive. Our findings, when coupled with the risk inherent in clonidine overdose, suggest that further research into the identification and treatment of clonidine abuse among methadone patients is warranted. (C) 1998 Elsevier Science Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 01/10/20 alle ore 04:34:27