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Titolo:
CORRELATION BETWEEN SYMPTOM FATIGUE AND MUSCULAR FATIGUE IN MULTIPLE-SCLEROSIS
Autore:
IRIARTE J;
Indirizzi:
UNIV NAVARRA,UNIV NAVARRA CLIN,DEPT NEUROL,AVE PIO XII 36 NAVARRA 31008 SPAIN
Titolo Testata:
European journal of neurology
fascicolo: 6, volume: 5, anno: 1998,
pagine: 579 - 585
SICI:
1351-5101(1998)5:6<579:CBSFAM>2.0.ZU;2-6
Fonte:
ISI
Lingua:
ENG
Soggetto:
MOTOR EVOKED-POTENTIALS; MUSCLE FATIGUE; QUANTITATIVE ASSESSMENT; NEUROLOGICAL DISORDERS; NEUROMUSCULAR FATIGUE; VISUAL FATIGUE; LIMB MUSCLES; DEPRESSION; 3,4-DIAMINOPYRIDINE; 4-AMINOPYRIDINE;
Keywords:
MULTIPLE SCLEROSIS; MUSCULAR FATIGUE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
60
Recensione:
Indirizzi per estratti:
Citazione:
J. Iriarte, "CORRELATION BETWEEN SYMPTOM FATIGUE AND MUSCULAR FATIGUE IN MULTIPLE-SCLEROSIS", European journal of neurology, 5(6), 1998, pp. 579-585

Abstract

The symptom of fatigue is a frequent complaint in multiple sclerosis (MS) patients. Signs of fatigability have been documented in these patients as well. However, correlation with signs of objective fatigue had not been clarified in MS. The aim of this study was to ascertain theexistence of muscular fatigue in multiple sclerosis patients, and to find out if there is a correlation between the subjective symptom of fatigue and muscular fatigue. Fifty MS patients and 50 age and sex matched volunteers were studied using isometric and isotonic tests using the dominant hand. Strength was studied in the baseline condition and also after recovery of either an isotonic (experiment A) or isometric effort (experiment B), Maximum strength, strength in relationship to weight, slope of fatigability in 11 consecutive contractions, and strength and duration of a maximum effort were calculated. Fatigue as a symptom was measured using the Fatigue Severity Scale (FSS) and the Fatigue Descriptive Scale (FDS). Non-parametric techniques were used for thestatistical analysis. Patients with MS had less isometric and isotonic strength, but the recovery was the same as recovery in the control group. There was a negative linear correlation between the symptom of fatigue and the baseline strength. In conclusion, this study supports the existence of signs of muscular fatigue in MS patients. However, therecovery after exercise is normal. The correlation between the baseline scores in strength and the symptom of fatigue suggest that the samecause (probably pyramidal deficits) may be involved in both of them. Eur J Neurol 5:579-585 (C) 1998 Lippincott Williams & Wilkins.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/01/20 alle ore 09:49:56