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Titolo:
HOSPITAL DAYS IN CLOZAPINE-TREATED PATIENTS
Autore:
DICKSON RA; DALBY JT; WILLIAMS R; WARDEN SJ;
Indirizzi:
PETER LOUGHEED CTR,CARNAT CTR,3500 26TH AVE NE CALGARY AB T1Y 6J4 CANADA CALGARY GEN HOSP,SPECIALIZED PROGRAMS DIV,REG CLIN DEPT PSYCHIAT,CARNAT CTR,PETER LOUGHEED CTR CALGARY AB CANADA CALGARY GEN HOSP,REG CLIN DEPT PSYCHOL,PETER LOUGHEED CTR CALGARY AB CANADA UNIV CALGARY CALGARY AB T2N 1N4 CANADA
Titolo Testata:
Canadian journal of psychiatry
fascicolo: 9, volume: 43, anno: 1998,
pagine: 945 - 948
SICI:
0706-7437(1998)43:9<945:HDICP>2.0.ZU;2-0
Fonte:
ISI
Lingua:
ENG
Soggetto:
NEUROLEPTIC-RESISTANT SCHIZOPHRENIA; REFRACTORY SCHIZOPHRENIA; COST-EFFECTIVENESS;
Keywords:
SCHIZOPHRENIA; CLOZAPINE; OUTCOME MEASURES; HOSPITAL DAYS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Physical, Chemical & Earth Sciences
Science Citation Index Expanded
Citazioni:
14
Recensione:
Indirizzi per estratti:
Citazione:
R.A. Dickson et al., "HOSPITAL DAYS IN CLOZAPINE-TREATED PATIENTS", Canadian journal of psychiatry, 43(9), 1998, pp. 945-948

Abstract

Objective: To examine inpatient hospital days used by a group of patients with treatment-resistant schizophrenia for 3 years before and 3 years after clozapine initiation. Method: A retrospective chart review of 26 consecutive admissions to an outpatient clozapine clinic was conducted for a 6-year period. The total number of hospital days was recorded. Results: Patients separated into 3 groups: those who used clozapine for 3 uninterrupted years (N = 11, 42.3%), those who interrupted but resumed clozapine and continued on to 3 years (N = 4, 15.4%), and those who abandoned clozapine treatment (N = 11, 42.3%). Only the groupthat was continuously on clozapine showed a decline in percentage of inpatient days during the 3-year follow-up period. Three of the IJ patients who discontinued clozapine died during the posttreatment period:2 suicides and 1 ''death by misadventure. '' Conclusions: Continuous clozapine treatment significantly reduces days in hospital; this reduction was sustained throughout 3 years' follow-up. While the sample sizeis small, all patients were tracked over a 6-year period, and both drug continuers and dropouts were followed. The reduction in inpatient days may be lost if patients stop and then restart clozapine. For patients who do not respond to or abandon trials of clozapine, there is an urgent need to develop more effective treatment strategies.

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Documento generato il 05/12/20 alle ore 01:19:24