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Titolo:
ACTIVATION PATTERNS OF COVERT WORD GENERATION DETECTED BY FMRI - COMPARISON WITH 3D PET
Autore:
SADATO N; YONEKURA Y; YAMADA H; NAKAMURA S; WAKI A; ISHII Y;
Indirizzi:
FUKUI MED UNIV,BIOMED IMAGING RES CTR,23 SHIMOAIZUKI FUKUI 91011 JAPAN FUKUI MED UNIV,DEPT RADIOL FUKUI 91011 JAPAN
Titolo Testata:
Journal of computer assisted tomography
fascicolo: 6, volume: 22, anno: 1998,
pagine: 945 - 952
SICI:
0363-8715(1998)22:6<945:APOCWG>2.0.ZU;2-9
Fonte:
ISI
Lingua:
ENG
Soggetto:
POSITRON-EMISSION TOMOGRAPHY; HUMAN BRAIN; SENSORY STIMULATION; FUNCTIONAL MRI; CORTEX; COMPENSATION; PERFORMANCE; RETRIEVAL; ANATOMY; IMAGES;
Keywords:
MAGNETIC RESONANCE IMAGING, FUNCTIONAL (FMRI); EMISSION COMPUTED TOMOGRAPHY; IMAGE REGISTRATION; BRAIN, METABOLISM;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
36
Recensione:
Indirizzi per estratti:
Citazione:
N. Sadato et al., "ACTIVATION PATTERNS OF COVERT WORD GENERATION DETECTED BY FMRI - COMPARISON WITH 3D PET", Journal of computer assisted tomography, 22(6), 1998, pp. 945-952

Abstract

Purpose: The aim of our study was to compare the activation patterns of higher cognitive function detected by functional MRI (fMRI) with those by (H2O)-O-15 positron emission tomography (PET). Method: Activation studies with both modalities were performed in six normal Volunteers with identical covert word generation tasks and statistical analysis. For PET, each subject had five rest scans and five task scans at 10 min intervals, fMRI was performed with a 1.5 T magnet using T2-weighted echo planar sequences. Each scanning session consisted of two rest and two task periods of 30 s each, alternating rest and task. Results:In group analysis, the activation patterns on both PET and fMRI were similar, whereas the deactivation patterns differed, presumably due tothe noise of fMRI. In single-subject analysis, PET showed fewer activated areas and fMRI showed more areas of activation than in group analysis. Conclusion: fMRI has an advantage over 3D PET in its better signal-to-noise ratio for detecting change in neuronal activity for higherbrain function.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 03/04/20 alle ore 14:10:19