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Titolo:
COURSE AND TREATMENT OF ATYPICAL DEPRESSION
Autore:
NIERENBERG AA; ALPERT JE; PAVA J; ROSENBAUM JF; FAVA M;
Indirizzi:
MASSACHUSETTS GEN HOSP,DEPRESS CLIN & RES PROGRAM,WACC 815,15 PARKMANST BOSTON MA 02114
Titolo Testata:
The Journal of clinical psychiatry
, volume: 59, anno: 1998, supplemento:, 18
pagine: 5 - 9
SICI:
0160-6689(1998)59:<5:CATOAD>2.0.ZU;2-7
Fonte:
ISI
Lingua:
ENG
Soggetto:
ANTIDEPRESSANT DRUGS; MAJOR DEPRESSION; BIPOLAR; PHENELZINE; UNIPOLAR; DISORDER; EPISODES; SUBTYPES; PLACEBO;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Physical, Chemical & Earth Sciences
Physical, Chemical & Earth Sciences
Science Citation Index Expanded
Citazioni:
34
Recensione:
Indirizzi per estratti:
Citazione:
A.A. Nierenberg et al., "COURSE AND TREATMENT OF ATYPICAL DEPRESSION", The Journal of clinical psychiatry, 59, 1998, pp. 5-9

Abstract

Atypical depression is the most common form of depression in outpatients, but compared with melancholia, Little is known about its comorbidity, course, and treatment. Beyond the well-characterized constellation of symptoms that define atypical depression (mood reactivity, hypersomnia, leaden paralysis, hyperphagia, and rejection sensitivity), specific Axis I and II comorbid conditions may differentiate atypical fromother depressed patients. Similarly, age at onset, duration of episodes, frequency of relapses and recurrences, and frequency of complete remission in atypical depression may be different. It has not even beenestablished If atypical depression is a stable subtype or if it is just one of several forms of depression that an individual may express during a lifetime of recurrent depressions. Monoamine oxidase inhibitors (MAOIs) are superior to tricyclic antidepressants (TCAs) for the treatment of atypical depression, but few studies have compared MAOIs to the newer generation of antidepressants (SSRIs, bupropion, venlafaxine, nefazodone, and mirtazapine). Because of the favorable benefit/risk ratio, clinicians tend to use these newer antidepressants for all outpatients, including those with atypical depression, even though the literature is limited. A review and critique of the relevant literature on atypical depression will be presented.

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Documento generato il 21/09/20 alle ore 05:58:42