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Titolo:
EFFECTIVENESS OF PROSTAGLANDIN E-2 INTRACERVICAL GEL (PREPIDIL), WITHIMMEDIATE OXYTOCIN, VERSUS VAGINAL INSERT (CERVIDIL) FOR INDUCTION OFLABOR
Autore:
STEWART JD; RAYBURN WF; FARMER KC; LILES EM; SCHIPUL AH; STANLEY JR;
Indirizzi:
UNIV OKLAHOMA,HLTH SCI CTR,COLL MED,DEPT OBSTET & GYNECOL,SECT MATERNAL FETAL MED,POB 26901 OKLAHOMA CITY OK 73190 UNIV OKLAHOMA,CTR HLTH SCI,COLL PHARM,DEPT PHARM ADM NORMAN OK 73019
Titolo Testata:
American journal of obstetrics and gynecology
fascicolo: 5, volume: 179, anno: 1998,
pagine: 1175 - 1180
SICI:
0002-9378(1998)179:5<1175:EOPEIG>2.0.ZU;2-4
Fonte:
ISI
Lingua:
ENG
Soggetto:
CONTROLLED-RELEASE; PESSARY; TERM;
Keywords:
LABOR INDUCTION; PROSTAGLANDIN E-2; OXYTOCIN; CERVICAL RIPENING; COST EFFECTIVENESS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
18
Recensione:
Indirizzi per estratti:
Citazione:
J.D. Stewart et al., "EFFECTIVENESS OF PROSTAGLANDIN E-2 INTRACERVICAL GEL (PREPIDIL), WITHIMMEDIATE OXYTOCIN, VERSUS VAGINAL INSERT (CERVIDIL) FOR INDUCTION OFLABOR", American journal of obstetrics and gynecology, 179(5), 1998, pp. 1175-1180

Abstract

OBJECTIVE: Our purpose was to compare the effectiveness of labor induction with use of prostaglandin E-2 either as an intracervical gel (Prepidil), with immediate oxytocin, or as a sustained-release vaginal insert (Cervidil) with subsequent oxytocin as needed. STUDY DESIGN: Hospitalized patients at greater than or equal to 37 weeks' gestation requiring labor induction and having an unfavorable cervix (Bishop score less than or equal to 6) were randomly assigned to receive either Prepidil or Cervidil. Oxytocin was begun immediately after Prepidil placement or 30 minutes after removal of the Cervidil insert if needed. RESULTS: Of the 150 patients, there were no differences in demographics andeventual pregnancy outcomes between the Prepidil group (n = 77) and the Cervidil group (n = 73). Those pregnancies receiving the Prepidil-immediate oxytocin regimen were delivered sooner than those receiving the Cervidil among nulliparous (11.3 +/- 7.3 hours vs 25.2 +/- 12.5 hours, P < .001) and multiparous (8.4 +/- 7.8 hours vs 18.4 +/- 7.2 hours, P < .001)women. The mean cost savings, which favored the Prepidil-immediate oxytocin regimen, was $458 (range $204 to $630) per patient. CONCLUSION: Compared with Cervidil, the Prepidil-immediate oxytocin regimen resulted in a shorter induction-to-vaginal delivery interval and in more hospital cost savings without increasing adverse outcomes.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 26/09/20 alle ore 11:49:38