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Titolo:
GENE-KNOCKOUT MICE WITH ABNORMAL EPIDERMAL AND HAIR FOLLICULAR DEVELOPMENT
Autore:
YAMANISHI K;
Indirizzi:
KYOTO PREFECTURAL UNIV MED,DEPT DERMATOL,KAMIGYO KU KYOTO 6028566 JAPAN
Titolo Testata:
Journal of dermatological science
fascicolo: 2, volume: 18, anno: 1998,
pagine: 75 - 89
SICI:
0923-1811(1998)18:2<75:GMWAEA>2.0.ZU;2-K
Fonte:
ISI
Lingua:
ENG
Soggetto:
CORNIFIED CELL-ENVELOPE; JUNCTIONAL EPIDERMOLYSIS-BULLOSA; VULGARIS ANTIGEN DESMOGLEIN-3; STRATIFIED SQUAMOUS EPITHELIA; SITE-SPECIFIC RECOMBINATION; KERATINOCYTE GROWTH-FACTOR; PIG-A GENE; TRANSGENIC MICE; SKIN DEVELOPMENT; ACID RECEPTOR;
Keywords:
GENE TARGETING; KNOCKOUT MICE; SKIN DEVELOPMENT; KERATINOCYTES; EPIDERMIS; HAIR FOLLICLES;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
108
Recensione:
Indirizzi per estratti:
Citazione:
K. Yamanishi, "GENE-KNOCKOUT MICE WITH ABNORMAL EPIDERMAL AND HAIR FOLLICULAR DEVELOPMENT", Journal of dermatological science, 18(2), 1998, pp. 75-89

Abstract

In the past 8 years, analysis of mutant mice and development of gene-knockout mice have provided important new avenues to identify disease genes and to study gene functions in the skin. Targeted disruption of genes in mice is a powerful means to investigate the contribution of aparticular gene defect to a given phenotype and to generate murine models of hereditary skin disorders with epidermal and hair follicular abnormalities. This review summarizes recent studies of knockout mouse models with abnormalities in epidermal and/or hair follicular development. (C) 1998 Elsevier Science Ireland Ltd. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/11/20 alle ore 16:18:11