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Titolo:
RELATIONSHIPS BETWEEN CSF NEUROPEPTIDES AND TEMPERAMENT TRAITS IN SUICIDE ATTEMPTERS
Autore:
ENGSTROM G; WESTRIN A; EKMAN R; TRASKMANBENDZ L;
Indirizzi:
MALMO UNIV HOSP,DEPT COMMUNITY MED S-20502 MALMO SWEDEN UNIV LUND HOSP,DEPT CLIN NEUROSCI,DIV PSYCHIAT S-22185 LUND SWEDEN UNIV GOTHENBURG,MOLNDAL HOSP,DEPT NEUROCHEM GOTHENBURG SWEDEN
Titolo Testata:
Personality and individual differences
fascicolo: 1, volume: 26, anno: 1999,
pagine: 13 - 19
SICI:
0191-8869(1999)26:1<13:RBCNAT>2.0.ZU;2-O
Fonte:
ISI
Lingua:
ENG
Soggetto:
CORTICOTROPIN-RELEASING FACTOR; DEXAMETHASONE SUPPRESSION TEST; PEPTIDE-YY; DEPRESSION; PERSONALITY; IMMUNOREACTIVITY; SCHIZOPHRENIA; VULNERABILITY; METABOLITES; ASSOCIATION;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Physical, Chemical & Earth Sciences
Citazioni:
34
Recensione:
Indirizzi per estratti:
Citazione:
G. Engstrom et al., "RELATIONSHIPS BETWEEN CSF NEUROPEPTIDES AND TEMPERAMENT TRAITS IN SUICIDE ATTEMPTERS", Personality and individual differences, 26(1), 1999, pp. 13-19

Abstract

Depressive disorders have been associated with deviances in the levels of various neuropeptide like immunoreactivities in the cerebrospinalfluid (CSF), and also with specific temperament traits. With the hypothesis that neuropeptides in CSF might be associated with specific temperament traits, we studied a sample of 40 hospitalized suicide attempters. They all filled in the Eysenck Personality Questionnaire (EPQ) in combination with the impulsiveness scale from the Impulsiveness-Venturesomeness-Empathy (IVE) inventory. Corticotropin releasing hormone (CRH), neuropeptide Y (NPY), beta-endorphin, gamma-melanocyte stimulating hormone (gamma(2)-MSH), somatostatin, peptide YY and delta-sleep inducing peptide (DSIP) like immuno-reactivities were measured in lumbarCSF. Contrary to our hypotheses, there was no relationship between neuroticism and CRH or NPY. Psychoticism and impulsiveness correlated positively and significantly with gamma(2)-MSH, a peptide associated with increased sympathetic drive. The other neuropeptides showed no significant associations with temperament. The relationship between gamma(2)-MSH and the psychoticism dimension needs to be replicated and studies of healthy subjects and nonsuicidal patients would be of interest. (C) 1998 Elsevier Science Ltd. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 17/01/20 alle ore 20:08:29