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Titolo:
DENTAL AND GINGIVAL PAIN AS SIDE-EFFECTS OF NIACIN THERAPY
Autore:
LEIGHTON RF; GORDON NF; SMALL GS; DAVIS WJ; WARD ES;
Indirizzi:
5 AMBERLY COURT SAVANNAH GA 31411 MED COLL OHIO TOLEDO OH 43699 ST JOSEPHS CANDLER HLTH SYST,CTR HEART DIS PREVENT SAVANNAH GA 00000 UNIV MICHIGAN,DEPT ORAL & MAXILLOFACIAL SURG ANN ARBOR MI 48109 MERCER UNIV,SCH PHARM,DEPT PHARM PRACTICE MACON GA 31207
Titolo Testata:
Chest
fascicolo: 5, volume: 114, anno: 1998,
pagine: 1472 - 1474
SICI:
0012-3692(1998)114:5<1472:DAGPAS>2.0.ZU;2-U
Fonte:
ISI
Lingua:
ENG
Soggetto:
NICOTINIC-ACID; LIPOPROTEIN LP(A); MORTALITY; DISEASE; DRUG;
Keywords:
DYSLIPIDEMIA; NIACIN; SIDE EFFECTS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
9
Recensione:
Indirizzi per estratti:
Citazione:
R.F. Leighton et al., "DENTAL AND GINGIVAL PAIN AS SIDE-EFFECTS OF NIACIN THERAPY", Chest, 114(5), 1998, pp. 1472-1474

Abstract

Two 65-year-old white men with coronary heart disease, given niacin therapy for dyslipidemia for 5 months, developed intense dental and gingival pain that was associated with increases in dose and that was relieved,vith discontinuance of niacin treatment. One individual who tookcrystalline niacin had beneficial effects on lipid levels, while the other person who took a delayed release preparation had little lipid effect. The cause of these previously unreported side effects of niacintherapy is uncertain but may be related to prostaglandin-mediated vasodilatation, hyperalgesia of sensory nerve receptors, and potentiationof inflammation in the gingiva with referral of pain to the teeth.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 27/11/20 alle ore 22:18:45