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Titolo:
SUCCESSFUL MANAGEMENT OF SEVERE IDIOPATHIC THROMBOCYTOPENIA IN THE 2ND-TRIMESTER OF PREGNANCY
Autore:
ANTSAKLIS A; PAPAGEORGIU I; SINDOS M; KATSIMANIS E; KARAISKAKIS P; MICHALAS S;
Indirizzi:
UNIV ATHENS,DEPT OBSTET & GYNECOL,DIV MATERNAL FETAL MED,11 LAMPSAKOUST GR-11528 ATHENS GREECE UNIV ATHENS,SCH MED,DEPT OBSTET & GYNECOL 1,DIV MATERNAL FETAL MED,ALEXANDRA HOSP GR-11527 ATHENS GREECE
Titolo Testata:
Fetal diagnosis and therapy
fascicolo: 4, volume: 13, anno: 1998,
pagine: 233 - 235
SICI:
1015-3837(1998)13:4<233:SMOSIT>2.0.ZU;2-U
Fonte:
ISI
Lingua:
ENG
Soggetto:
RISK;
Keywords:
IDIOPATHIC THROMBOCYTOPENIA; PREGNANCY; ANTIPLATELET ANTIBODIES;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
9
Recensione:
Indirizzi per estratti:
Citazione:
A. Antsaklis et al., "SUCCESSFUL MANAGEMENT OF SEVERE IDIOPATHIC THROMBOCYTOPENIA IN THE 2ND-TRIMESTER OF PREGNANCY", Fetal diagnosis and therapy, 13(4), 1998, pp. 233-235

Abstract

This paper describes a case of severe idiopathic thrombocytopenia in a primigravida. The disorder became symptomatic at 22 weeks gestation with a platelet count of 20,000/mu l. The existence of chronic idiopathic thrombocytopenia under remission was strongly suspected, but couldnot be documented. The patient was treated with oral corticosteroids over a period of 7 weeks. During this period, she also had three cycles of high-dose intravenous globulin. This treatment produced a transient improvement, but the platelet count fell to 4,000/mu l by the 29th gestational week. Caesarean section was carried out for maternal indication a week later, following a fourth intensified course of gamma-globulin, coupled with platelet transfusions and low-dose vinblastine. Splenectomy was not performed. Potentially life-threatening thrombocytopenia persisted for 6 weeks post partum. Despite the presence of circulating antiplatelet globulin in the maternal blood and the antenatal use of vinblastine, the infant was entirely unaffected and thrived.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 03/04/20 alle ore 13:22:58