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Titolo:
DIFFERENT ENERGY METABOLITE PATTERN BETWEEN UTERINE SMOOTH-MUSCLE ANDSTRIATED RECTUS MUSCLE IN TERM PREGNANT-WOMEN
Autore:
STEINGRIMSDOTTIR T; RONQUIST G; ULMSTEN U; WALDENSTROM A;
Indirizzi:
UNIV UPPSALA HOSP,DEPT CLIN CHEM S-75185 UPPSALA SWEDEN UNIV UPPSALA HOSP,DEPT CLIN CHEM S-75185 UPPSALA SWEDEN UNIV UPPSALA HOSP,DEPT OBSTET & GYNECOL S-75185 UPPSALA SWEDEN UMEA UNIV HOSP,DEPT CARDIOL S-90185 UMEA SWEDEN
Titolo Testata:
European journal of obstetrics, gynecology, and reproductive biology
fascicolo: 2, volume: 62, anno: 1995,
pagine: 241 - 245
SICI:
0301-2115(1995)62:2<241:DEMPBU>2.0.ZU;2-T
Fonte:
ISI
Lingua:
ENG
Soggetto:
FATTY-ACIDS; ADENOSINE; RECEPTORS; CHARGE; UTERUS;
Keywords:
UTERUS, HUMAN; PREGNANCY; STRIATED MUSCLE; GLUCOSE; ADENOSINE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
17
Recensione:
Indirizzi per estratti:
Citazione:
T. Steingrimsdottir et al., "DIFFERENT ENERGY METABOLITE PATTERN BETWEEN UTERINE SMOOTH-MUSCLE ANDSTRIATED RECTUS MUSCLE IN TERM PREGNANT-WOMEN", European journal of obstetrics, gynecology, and reproductive biology, 62(2), 1995, pp. 241-245

Abstract

Objective: To study the energy metabolite pattern in term pregnant myometrium and to compare it with that of a striated skeletal muscle. Study design: Metabolites of carbohydrates, triglycerides and nucleotides were determined in biopsies from myometrium and rectus abdominis muscle from ten healthy term pregnant women before onset of labour. The metabolite concentrations in the two types of muscle were compared by two tailed Student's t-test for paired values and correlations were calculated by Pearsson's correlation test. Results: Comparison of the twomuscle types revealed a higher concentration of glucose and a higher lactate/pyruvate ratio in the myometrium but a lower concentration of triglyceride metabolites. Adenosine was found in 36-fold higher concentration in the uterine compared with the rectus muscle and an inverse relationship between adenosine and glucose concentrations was observedin the myometrium. Conclusion: The results indicated that the pregnant uterine smooth muscle utilized glucose as the principal nutritive metabolite rather than lipids and that the anaerobic pathway of the glucose metabolism was more active in the myometrium compared with the striated rectus muscle. Also, it is suggested that glucose has a criticalrole as the principal fuel for ATP formation and the involvement of the adenylate kinase and 5'-nucleotidase reactions in any event of glucose shortage.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/11/20 alle ore 00:45:31