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Titolo:
NEPHROLITHIASIS AND RISK OF HYPERTENSION IN WOMEN
Autore:
MADORE F; STAMPFER MJ; WILLETT WC; SPEIZER FE; CURHAN GC;
Indirizzi:
BRIGHAM & WOMENS HOSP,CHANNING LAB,DEPT MED,181 LONGWOOD AVE BOSTON MA 02115 BRIGHAM & WOMENS HOSP,CHANNING LAB,DEPT MED BOSTON MA 02115 BRIGHAM & WOMENS HOSP,DIV RENAL BOSTON MA 02115 HARVARD UNIV,SCH MED CAMBRIDGE MA 02138 HARVARD UNIV,SCH PUBL HLTH,DEPT EPIDEMIOL CAMBRIDGE MA 02138 HARVARD UNIV,SCH PUBL HLTH,DEPT NUTR CAMBRIDGE MA 02138 HARVARD UNIV,SCH PUBL HLTH,DEPT ENVIRONM HLTH CAMBRIDGE MA 02138 MASSACHUSETTS GEN HOSP,MED SERV,RENAL UNIT BOSTON MA 02114
Titolo Testata:
American journal of kidney diseases
fascicolo: 5, volume: 32, anno: 1998,
pagine: 802 - 807
SICI:
0272-6386(1998)32:5<802:NAROHI>2.0.ZU;2-I
Fonte:
ISI
Lingua:
ENG
Soggetto:
URINARY CALCIUM EXCRETION; BLOOD-PRESSURE; KIDNEY-STONES; DIETARY CALCIUM; UNITED-STATES; METABOLISM; SODIUM; RAT; HYPERCALCIURIA; QUESTIONNAIRE;
Keywords:
BLOOD PRESSURE; KIDNEY STONES; PROSPECTIVE STUDY; EPIDEMIOLOGY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
39
Recensione:
Indirizzi per estratti:
Citazione:
F. Madore et al., "NEPHROLITHIASIS AND RISK OF HYPERTENSION IN WOMEN", American journal of kidney diseases, 32(5), 1998, pp. 802-807

Abstract

Cross-sectional and prospective studies of men suggest a positive association between nephrolithiasis and hypertension. However, this association remains controversial in women. We conducted a prospective study of the relation between nephrolithiasis and the risk for hypertension in the Nurses' Health Study, a cohort of 89,376 women aged 34 to 59 years in 1980. Information on the history of nephrolithiasis, physician-diagnosed hypertension, and other relevant exposures was obtained bybiennial mailed questionnaire. A history of nephrolithiasis before 1980 was reported by 2,558 women (2.9%), and a history of hypertension was reported by 11,883 women (13.3%). Among women without hypertension before 1980, 12,540 women reported a new diagnosis of hypertension between 1980 and 1992, during 711,039 person-years of follow-up. Comparedwith those without a history of nephrolithiasis, the age-adjusted relative risk (RR) for incident hypertension in women with such a historywas 1.36 (95% confidence interval [CI], 1.20 to 1.43). After further adjustment for body mass index (BMI) and the intake of calcium, sodium, potassium, magnesium, caffeine, and alcohol, the RR was only slightly attenuated (RR = 1.24; 95% CI, 1.13 to 1.37). In contrast, the occurrence of incident nephrolithiasis during follow-up was similar in women with hypertension at baseline compared with women without (adjusted odds ratio [OR] = 1.01; 95% CI, 0.85 to 1.20). These data are consistent with the results obtained in men and support the hypothesis that a history of nephrolithiasis is associated with an increased risk for subsequent hypertension. Dietary factors, such as the intake of calcium,sodium, and potassium, do not explain this association. Unidentified pathogenic mechanisms common to nephrolithiasis and hypertension may be responsible for the development of both disorders. (C) 1998 by the National Kidney Foundation, Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 01/12/20 alle ore 11:03:23