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Titolo:
COMPARATIVE ASPECTS OF MEIOTIC CELL-CYCLE CONTROL IN MAMMALS
Autore:
ALBERTINI DF; CARABATSOS MJ;
Indirizzi:
TUFTS UNIV,SCH MED,DEPT ANAT & CELLULAR BIOL,136 HARRISON AVE BOSTON MA 02111
Titolo Testata:
Journal of molecular medicine
fascicolo: 12, volume: 76, anno: 1998,
pagine: 795 - 799
SICI:
0946-2716(1998)76:12<795:CAOMCC>2.0.ZU;2-X
Fonte:
ISI
Lingua:
ENG
Soggetto:
MOUSE OOCYTES; PARTHENOGENETIC DEVELOPMENT; MICROTUBULE DYNAMICS; COMPETENCE; ACQUISITION; ACCUMULATION; P34(CDC2); OVARY; MATURATION; ACTIVATION;
Keywords:
MEIOSIS; CELL CYCLE; GAMATES; FOLLICULOGENESIS;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
26
Recensione:
Indirizzi per estratti:
Citazione:
D.F. Albertini e M.J. Carabatsos, "COMPARATIVE ASPECTS OF MEIOTIC CELL-CYCLE CONTROL IN MAMMALS", Journal of molecular medicine, 76(12), 1998, pp. 795-799

Abstract

This review examines the mechanisms of cell cycle control in mammalian germ cells with respect to species-specific variations in reproductive strategies. While sex-specific variants are evidenced at the level of checkpoint controls, the timing of meiotic progression, and the modulation of meiosis by hormonal cues, local somatic cell influences impose a hierarchical order to both the initiation and completion of gametogenesis. In the particular case of meiosis in females the rules governing entry into meiotic prophase during gonadal development are generally conserved. In contrast, the regulation of meiotic arrest in developing ovarian follicles, the reinitiation of meiosis at ovulation, andthe completion of meiosis upon fertilization involves changes in boththe cell cycle machinery and execution of external cues. The overall efficiency of meiotic progression is determined by inputs, mediated bycell contact and/or growth factor, which coordinate oogenesis with folliculogenesis and ensure appropriate and species-specific ovulatory outputs (monovular or polyovular). How mechanisms of meiotic cell cyclecontrol can be exploited to improve gamete quality or interfere with fertility is discussed.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 20/09/20 alle ore 05:00:21