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Titolo:
LIVER RESECTION OF NONCOLORECTAL SECONDARIES
Autore:
LINDELL G; OHLSSON B; SAARELA A; ANDERSSON R; TRANBERG KG;
Indirizzi:
LUND UNIV,DEPT SURG S-22185 LUND SWEDEN
Titolo Testata:
Journal of surgical oncology
fascicolo: 2, volume: 69, anno: 1998,
pagine: 66 - 70
SICI:
0022-4790(1998)69:2<66:LRONS>2.0.ZU;2-X
Fonte:
ISI
Lingua:
ENG
Soggetto:
HEPATIC RESECTION; PATIENT SELECTION; METASTASES; EXPERIENCE; TUMORS; NEOPLASMS; SURVIVAL;
Keywords:
HEPATIC RESECTION; LIVER METASTASES; NONCOLORECTAL; ENDOCRINE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
24
Recensione:
Indirizzi per estratti:
Citazione:
G. Lindell et al., "LIVER RESECTION OF NONCOLORECTAL SECONDARIES", Journal of surgical oncology, 69(2), 1998, pp. 66-70

Abstract

Background and Objectives: Hepatic resection of noncolorectal metastases appears to be performed with increasing frequency. Reported experience is limited and indications are controversial. Methods: Retrospective review of curative hepatic resection in 32 patients (median age 58years) during 1970-1995. The primary tumor was a carcinoid in seven patients, other endocrine tumor in five patients, malignant melanoma inthree patients, stomach cancer in three patients, exocrine pancreaticcancer in two patients, gynecological cancer in two patients, sarcomain two patients, and miscellaneous in eight patients. Seven patients (22%) had bilobar disease and 12 patients (38%) had extrahepatic growth. Results: Median survival was 32 months, and 5-year actuarial survival rate was 36% (including operative mortality). Median survival in the endocrine (n = 12) and nonendocrine (n = 20) groups was 72 and 18 months, respectively (corresponding 5-year survival rates were 56 and 25%) (P = 0.16). Prognostic factors could not be established in either group. It is, however, noteworthy that no patient with nonendocrine secondaries and more than one liver tumor or extrahepatic disease survived for 5 years. Major complications were seen in eight patients (25%), including three postoperative deaths (operative mortality 9%) occurring during the first 5 years of the study period. Conclusions: Hepatic resection of metastases from endocrine primary tumors was followed by long-term survival in a substantial proportion of patients. Long-term survival for patients with nonendocrine tumors was observed only when there was a single liver tumor and no extrahepatic growth. Further experience is needed for definition of resection criteria. (C) 1998 Wiley-Liss, Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 10/04/20 alle ore 16:07:36