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Titolo:
SIGNALING AT THE SYNAPSE - REGULATION OF THE POSTSYNAPTIC RESPONSE TOQUANTAL TRANSMITTER RELEASE
Autore:
WALMSLEY B;
Indirizzi:
AUSTRALIAN NATL UNIV,JOHN CURTIN SCH MED RES,DIV NEUROSCI,SYNAPT STRUCT & FUNCT GRP CANBERRA ACT 0200 AUSTRALIA
Titolo Testata:
Immunology and cell biology
fascicolo: 5, volume: 76, anno: 1998,
pagine: 430 - 435
SICI:
0818-9641(1998)76:5<430:SATS-R>2.0.ZU;2-K
Fonte:
ISI
Lingua:
ENG
Soggetto:
ANTEROVENTRAL COCHLEAR NUCLEUS; CENTRAL NERVOUS-SYSTEM; EXCITATORY POSTSYNAPTIC CURRENTS; AMINO-ACID RECEPTORS; DEVELOPING CEREBELLUM; GLUTAMATE RECEPTORS; HIPPOCAMPAL SLICES; CALCIUM CHANNELS; NMDA RECEPTORS; AUDITORY SPACE;
Keywords:
POSTSYNAPTIC CURRENT; QUANTA; RECEPTOR; SYNAPSE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
55
Recensione:
Indirizzi per estratti:
Citazione:
B. Walmsley, "SIGNALING AT THE SYNAPSE - REGULATION OF THE POSTSYNAPTIC RESPONSE TOQUANTAL TRANSMITTER RELEASE", Immunology and cell biology, 76(5), 1998, pp. 430-435

Abstract

Communication between neurones in the central nervous system occurs at specialized synaptic contacts. The strength of a synaptic signal is precisely regulated, and modification of synaptic strength is important in complex brain functions such as learning, and in the formation ofappropriate neural maps during development. The fundamental building block of synaptic signalling is the post-synaptic current generated inresponse to the pre-synaptic release of a quantum of neurotransmitter. The present short review examines the factors that determine the quantal post-synaptic current, and provides direct evidence from a recentstudy in the author's laboratory that regulation of quantal size is important during development of excitatory transmission in the auditorysystem.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/07/20 alle ore 20:37:41