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Titolo:
LATE-ONSET UNILATERAL RENAL DYSFUNCTION COMBINED WITH NON-INSULIN-DEPENDENT DIABETES-MELLITUS AND BRONCHIAL-ASTHMA FOLLOWING ALLOGENEIC BONE-MARROW TRANSPLANTATION FOR ACUTE LYMPHOBLASTIC-LEUKEMIA IN A CHILD
Autore:
HIRAYAMA M; AZUMA E; KUMAMOTO T; QI J; KOBAYASHI M; KOMADA Y; INUI T; MIYAKE M; MUGISHIMA H; HAMAZAKI M; SAKURAI M;
Indirizzi:
MIE UNIV,SCH MED,DEPT CLIN IMMUNOL,2-174 EDOBASHI TSU MIE 514 JAPAN MIE UNIV,DEPT PEDIAT & CLIN IMMUNOL TSU MIE JAPAN MIE NATL HOSP,DEPT PEDIAT TSU MIE JAPAN OSAKA MED COLL,DEPT PEDIAT OSAKA JAPAN NIHON UNIV,DEPT PEDIAT TOKYO 102 JAPAN SHIZUOKA CHILDRENS HOSP,DEPT PATHOL SHIZUOKA JAPAN
Titolo Testata:
Bone marrow transplantation
fascicolo: 9, volume: 22, anno: 1998,
pagine: 923 - 926
SICI:
0268-3369(1998)22:9<923:LURDCW>2.0.ZU;2-G
Fonte:
ISI
Lingua:
ENG
Soggetto:
CHRONIC MYELOID-LEUKEMIA; RADIATION NEPHROPATHY; SPLENIC IRRADIATION;
Keywords:
BMT NEPHROPATHY; DIABETES MELLITUS; BRONCHIAL ASTHMA;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
17
Recensione:
Indirizzi per estratti:
Citazione:
M. Hirayama et al., "LATE-ONSET UNILATERAL RENAL DYSFUNCTION COMBINED WITH NON-INSULIN-DEPENDENT DIABETES-MELLITUS AND BRONCHIAL-ASTHMA FOLLOWING ALLOGENEIC BONE-MARROW TRANSPLANTATION FOR ACUTE LYMPHOBLASTIC-LEUKEMIA IN A CHILD", Bone marrow transplantation, 22(9), 1998, pp. 923-926

Abstract

We report a child with T cell acute lymphoblastic leukemia who developed late-onset multiple complications after allogeneic bone marrow transplantation from an HLA-matched sibling. The preparative regimen consisted of total body irradiation (TBI, 12 Gy), splenic irradiation (6 Gy) and cytosine arabinoside (3 g/m(2) x 10), Splenic irradiation was added because of persistent splenomegaly in spite of intensive chemotherapy. He developed bronchial asthma 11/2 years post transplant. He presented with microhematuria and proteinuria 41/2 years post-transplant,which were due to unilateral left renal dysfunction, He developed type II, non-insulin-dependent diabetes mellitus 8 years post-transplant. A biopsy from the left kidney was not compatible with diabetic nephropathy. All these complications appear to be independently related to BMT, particularly TBI and/or splenic irradiation.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/03/20 alle ore 19:04:17