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Titolo:
RANDOMIZED COMPARISON OF 4 TOOLS MEASURING OVERALL QUALITY-OF-LIFE INPATIENTS WITH ADVANCED CANCER
Autore:
SLOAN JA; LOPRINZI CL; KUROSS SA; MISER AW; OFALLON JR; MAHONEY MR; HELD IM; BRETSCHER ME; VAUGHT NL;
Indirizzi:
MAYO CLIN & MAYO FDN,200 1ST ST SW ROCHESTER MN 55905 MAYO CLIN & MAYO FDN ROCHESTER MN 55905 DULUTH COMMUNITY ONCOL PROGRAM DULUTH MN 00000 SIOUXLAND HEMATOL ONCOL ASSOCIATES SIOUX CITY IA 00000
Titolo Testata:
Journal of clinical oncology
fascicolo: 11, volume: 16, anno: 1998,
pagine: 3662 - 3673
SICI:
0732-183X(1998)16:11<3662:RCO4TM>2.0.ZU;2-A
Fonte:
ISI
Lingua:
ENG
Soggetto:
CELL LUNG-CANCER; BONE-MARROW TRANSPLANTATION; ADVANCED BREAST-CANCER; OF-LIFE; PALLIATIVE CARE; FUNCTIONAL ASSESSMENT; IMPORTANT DIFFERENCE; ADULT SURVIVORS; HEALTH-STATUS; PAIN;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
91
Recensione:
Indirizzi per estratti:
Citazione:
J.A. Sloan et al., "RANDOMIZED COMPARISON OF 4 TOOLS MEASURING OVERALL QUALITY-OF-LIFE INPATIENTS WITH ADVANCED CANCER", Journal of clinical oncology, 16(11), 1998, pp. 3662-3673

Abstract

Purpose: We report on a clinical trial developed to compare four different instruments that provide overall quality-of-life (QOL) scores, ranging from a simple, one-item instrument to more detailed instruments. Two issues addressed were (1) Will QOL tools suffer from missing data when used in a community-based cooperative group setting?, and (2) Are there additional data generated by a more detailed multiitem instrument over that provided by a single-item global QOL question? Materials and Methods: A four-arm randomized trial was designed to compare four instruments that provide overall QOL scores in patients with advanced colorectal cancer. Patients and physicians completed the single-itemSpitzer Uniscale (UNISCALE) at baseline and monthly. Patients were randomly assigned to complete, in addition, either the 22-item Functional Living Index-Cancer (FLIC), the five-item Spitzer QOL index (QLI), apicture-face scale (PICT), or nothing else. Results: A total of 128 patients were randomized. Greater than 90% complete QOL data were obtained. There was strong correlation, concordance, and criterion-related validity among ail four patient-completed tools. The UNISCALE had a greater decrease over time than did the FLIC (P = .005), which suggests a greater sensitivity; the UNISCALE was similar to the QLI and the PICT in this regard, Physicians provided lower UNISCALE scores than patients. Results supported the hypothesis that QOL is prognostic for survival. Conclusion: Patients can effectively complete QOL tools in a cooperative group setting with proper education of health care providers and patients. A simple single-item tool (UNISCALE) appears to be appropriate to obtain a measure of overall QOL. (C) 1998 by American Societyof Clinical Oncology.

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Documento generato il 26/11/20 alle ore 07:51:07