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Titolo:
ASYMPTOMATIC INTERNAL CAROTID-ARTERY STENOSIS DEFINED BY ULTRASOUND AND THE RISK OF SUBSEQUENT STROKE IN THE ELDERLY - THE CARDIOVASCULAR HEALTH STUDY
Autore:
LONGSTRETH WT; SHEMANSKI L; LEFKOWITZ D; OLEARY DH; POLAK JF; WOLFSON SK;
Indirizzi:
HARBORVIEW MED CTR,DEPT NEUROL,BOX 359775,315 9TH AVE SEATTLE WA 98104 UNIV WASHINGTON,DEPT NEUROL SEATTLE WA 98195 UNIV WASHINGTON,DEPT EPIDEMIOL SEATTLE WA 98195 UNIV WASHINGTON,DEPT BIOSTAT SEATTLE WA 98195 WAKE FOREST UNIV,DEPT NEUROL WINSTON SALEM NC 27109 TUFTS UNIV,NEW ENGLAND MED CTR,DEPT RADIOL BOSTON MA 02111 BRIGHAM & WOMENS HOSP,DEPT RADIOL BOSTON MA 02115 UNIV PITTSBURGH,SCH MED,DEPT SURG PITTSBURGH PA 00000 UNIV PITTSBURGH,SCH MED,DEPT NEUROSURG PITTSBURGH PA 15261
Titolo Testata:
Stroke
fascicolo: 11, volume: 29, anno: 1998,
pagine: 2371 - 2376
SICI:
0039-2499(1998)29:11<2371:AICSDB>2.0.ZU;2-3
Fonte:
ISI
Lingua:
ENG
Soggetto:
COST-EFFECTIVENESS; DUPLEX CRITERIA; ENDARTERECTOMY; PARAMETERS; DISEASE;
Keywords:
AGED; CAROTID ARTERY DISEASES; ULTRASONOGRAPHY, DOPPLER;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
19
Recensione:
Indirizzi per estratti:
Citazione:
W.T. Longstreth et al., "ASYMPTOMATIC INTERNAL CAROTID-ARTERY STENOSIS DEFINED BY ULTRASOUND AND THE RISK OF SUBSEQUENT STROKE IN THE ELDERLY - THE CARDIOVASCULAR HEALTH STUDY", Stroke, 29(11), 1998, pp. 2371-2376

Abstract

Background and Purpose-We sought in this study to relate carotid ultrasound findings in asymptomatic older adults to the 5-year risk of various cerebrovascular outcomes used in the Asymptomatic Carotid Atherosclerosis Study (ACAS). Methods-The Cardiovascular Health Study (CHS) is a longitudinal study of people 65 years and older. Analyses of internal carotid artery stenosis defined by multiple different cutoffs of peak systolic velocity, rather than one particular cutoff, were performed in the 5441 participants who underwent carotid ultrasound and lacked a history of transient ischemic attack or stroke. The 5-year risks of 7 cerebrovascular disease outcomes used in ACAS were estimated for each cutoff. Results-Associations with the 5-year risk of outcomes weresubstantially elevated only at cutoffs with high peak systolic velocities. In this population, the number of people with such high velocities was small. For example, with a cutoff of approximately 2.5 m/s, suggesting a stenosis of >70%, the 5-year risk of an ipsilateral fatal ornonfatal stroke was 5%, and only 0.5% of the group had velocities at least this high. Conclusions-In a group of older adults likely to participate in a screening program, as evidenced by willingness to participate in CHS, high peak systolic velocities consistent with high-grade carotid stenosis were uncommon and risk of subsequent cerebrovascular disease outcomes was relatively low. These findings do not suggest that similar populations of older adults would benefit from a program using ultrasound to screen for asymptomatic carotid stenosis.

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Documento generato il 27/11/20 alle ore 13:41:59