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Titolo:
ELEVATED LEVEL OF FOLLICULAR-FLUID VASCULAR ENDOTHELIAL GROWTH-FACTORIS A MARKER OF DIMINISHED PREGNANCY POTENTIAL
Autore:
FRIEDMAN CI; SEIFER DB; KENNARD EA; ARBOGAST L; ALAK B; DANFORTH DR;
Indirizzi:
OHIO STATE UNIV,DEPT OBSTET & GYNECOL,5TH FLOOR,MEANS HALL,1654 UPHAMDR COLUMBUS OH 43210
Titolo Testata:
Fertility and sterility
fascicolo: 5, volume: 70, anno: 1998,
pagine: 836 - 839
SICI:
0015-0282(1998)70:5<836:ELOFVE>2.0.ZU;2-P
Fonte:
ISI
Lingua:
ENG
Soggetto:
EXPRESSION; ANGIOGENESIS;
Keywords:
VEGF; FOLLICULAR FLUID; IN VITRO FERTILIZATION; OVARIAN AGING;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
11
Recensione:
Indirizzi per estratti:
Citazione:
C.I. Friedman et al., "ELEVATED LEVEL OF FOLLICULAR-FLUID VASCULAR ENDOTHELIAL GROWTH-FACTORIS A MARKER OF DIMINISHED PREGNANCY POTENTIAL", Fertility and sterility, 70(5), 1998, pp. 836-839

Abstract

Objective: To evaluate whether differences in follicular fluid vascular endothelial growth factor (FF VEGF) concentrations are observed between women achieving a clinical pregnancy and those failing to conceive. Design: Retrospective chart review and analysis of FF VEGF concentrations. Setting: University teaching center. Patient(s): Fifty-seven women less than or equal to 42 years of age undergoing follicular aspiration in preparation for IVF or GIFT. Intervention(s): Analysis of FF VEGF concentrations and chart review of a single IVF or GIFT cycle. Main Outcome Measure(s): Follicular fluid VEGF concentrations, clinical pregnancy rate, age, ampules of gonadotropins used. oocytes retrieved,peak estradiol serum concentrations, day 3 FSH levels, and fertilization rate. Result(s): Women who did not conceive had higher FF VEGF concentrations than women achieving a clinical pregnancy (4,409 + 2,387 versus 2,793 + 1,180 pg/mL: P < .001). A negative correlation was observed between FF VEGF concentrations and peak estradiol levels and number of oocytes retrieved. A positive correlation was found for FP VEGF and patient's age and ampules of gonadotropins used. Conclusion(s): Elevated FF VEGF concentrations are associated with poor conception ratesafter IVF or GIFT. (Fertil Steril(R) 1998;70:836-9. (C) 1998 by American Society for Reproductive Medicine.).

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 02/12/20 alle ore 07:43:13